User profiles for Nardnisa Sintupisut

Nardnisa Sintupisut

Ontario Institute for Cancer Research
Verified email at oicr.on.ca
Cited by 489

[HTML][HTML] Integrative pathway enrichment analysis of multivariate omics data

M Paczkowska, J Barenboim, N Sintupisut… - Nature …, 2020 - nature.com
Multi-omics datasets represent distinct aspects of the central dogma of molecular biology.
Such high-dimensional molecular profiles pose challenges to data interpretation and …

Functional proteomic and structural insights into molecular targets related to the growth inhibitory effect of tanshinone IIA on HeLa cells

…, PW Wang, ST Chen, TK Hsu, N Sintupisut… - …, 2010 - Wiley Online Library
Certain antitumor agents have recently been extracted from the roots of Salvia miltiorrhiza
Bunge. The diterpene derivative, tanshinone IIA, possesses cytotoxic activity against several …

[PDF][PDF] Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells

…, HF Chen, CY Chuang, SY Yang, PS Hou, N Sintupisut… - Stem cell reports, 2014 - cell.com
The mechanisms of transcriptional regulation underlying human primordial germ cell (PGC)
differentiation are largely unknown. The transcriptional repressor Prdm1/Blimp-1 is known to …

An integrative characterization of recurrent molecular aberrations in glioblastoma genomes

N Sintupisut, PL Liu, CH Yeang - Nucleic acids research, 2013 - academic.oup.com
Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor in
adults. Decades of investigations and the recent effort of the Cancer Genome Atlas (TCGA) …

[HTML][HTML] Analysis of spatial-temporal gene expression patterns reveals dynamics and regionalization in developing mouse brain

SJ Chou, C Wang, N Sintupisut, ZX Niou, CH Lin… - Scientific reports, 2016 - nature.com
Allen Brain Atlas (ABA) provides a valuable resource of spatial/temporal gene expressions
in mammalian brains. Despite rich information extracted from this database, current analyses …

Functional proteomics reveals the protective effects of saffron ethanolic extract on hepatic ischemia‐reperfusion injury

TL Pan, TH Wu, PW Wang, YL Leu, N Sintupisut… - …, 2013 - Wiley Online Library
Hepatic ischemia‐reperfusion (IR) injury is a common clinical problem and ROS may be a
contributing factor on IR injury. The current study evaluates the potential protective effect of …

Functional proteomics reveals hepatotoxicity and the molecular mechanisms of different forms of chromium delivered by skin administration

…, PW Wang, CC Chen, JY Fang, N Sintupisut - …, 2012 - Wiley Online Library
Chromium compounds are known to be associated with cytotoxicity and carcinogenicity when
applied via the skin. However, there is no perspective research to elucidate the causations …

[HTML][HTML] Author Correction: Integrative pathway enrichment analysis of multivariate omics data

M Paczkowska, J Barenboim, N Sintupisut… - nature …, 2022 - nature.com
In the published version of this paper, the members of the Pan-Cancer Analysis of Whole
Genomes (PCAWG) Consortium were listed in the Supplementary Information; however, these …

[HTML][HTML] Putative effectors for prognosis in lung adenocarcinoma are ethnic and gender specific

A Woolston, N Sintupisut, TP Lu, LC Lai, MH Tsai… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Lung adenocarcinoma possesses distinct patterns of EGFR/KRAS mutations between East
Asian and Western, male and female patients. However, beyond the well-known EGFR/…

Prospective highlights of serum glycoproteins in spontaneous tolerance after orthotopic liver transplantation

…, PW Wang, ST Chen, JY Fang, TK Hsu, N Sintupisut… - Clinica Chimica …, 2011 - Elsevier
BACKGROUND: We examined the effects and the mechanisms of serum glycoproteins on
spontaneous tolerance after orthotopic liver transplantation (OLT) between DA (RT-1 a ) and …