User profiles for Natalie M Clark
 | Natalie M ClarkComputational Scientist II, Broad Institute Verified email at broadinstitute.org Cited by 1181 |
[PDF][PDF] Nucleo-cytoplasmic partitioning of ARF proteins controls auxin responses in Arabidopsis thaliana
The phytohormone auxin plays crucial roles in nearly every aspect of plant growth and
development. The auxin response factor (ARF) transcription factor family regulates auxin-…
development. The auxin response factor (ARF) transcription factor family regulates auxin-…
Integrated multi-omics framework of the plant response to jasmonic acid
Understanding the systems-level actions of transcriptional responses to hormones provides
insight into how the genome is reprogrammed in response to environmental stimuli. Here, …
insight into how the genome is reprogrammed in response to environmental stimuli. Here, …
Predicting gene regulatory networks by combining spatial and temporal gene expression data in Arabidopsis root stem cells
…, AP Fisher, NM Clark… - Proceedings of the …, 2017 - National Acad Sciences
Identifying the transcription factors (TFs) and associated networks involved in stem cell
regulation is essential for understanding the initiation and growth of plant tissues and organs. …
regulation is essential for understanding the initiation and growth of plant tissues and organs. …
Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy
10.7554/eLife.14770.001 To understand complex regulatory processes in multicellular
organisms, it is critical to be able to quantitatively analyze protein movement and protein-protein …
organisms, it is critical to be able to quantitatively analyze protein movement and protein-protein …
Integrated omics reveal novel functions and underlying mechanisms of the receptor kinase FERONIA in Arabidopsis thaliana
The receptor kinase FERONIA (FER) is a versatile regulator of plant growth and development,
biotic and abiotic stress responses, and reproduction. To gain new insights into the …
biotic and abiotic stress responses, and reproduction. To gain new insights into the …
To the proteome and beyond: advances in single-cell omics profiling for plant systems
… Natalie M Clark , Natalie M Clark … Specifically, we developed a computational method
named Spatiotemporal Clustering and Inference of Omics Networks (SC-IONs), which …
named Spatiotemporal Clustering and Inference of Omics Networks (SC-IONs), which …
[HTML][HTML] Integrated omics networks reveal the temporal signaling events of brassinosteroid response in Arabidopsis
Brassinosteroids (BRs) are plant steroid hormones that regulate cell division and stress
response. Here we use a systems biology approach to integrate multi-omic datasets and unravel …
response. Here we use a systems biology approach to integrate multi-omic datasets and unravel …
Computational prediction of gene regulatory networks in plant growth and development
… , Jabeen S Ahmad 2 3 , Natalie M Clark 2 , Cranos M Williams 1 5 , Rosangela Sozzani 2 4
… MA de Luis Balaguer, AP Fisher, NM Clark, MG Fernandez-Espinosa, BK Möller, D. Weijers, …
… MA de Luis Balaguer, AP Fisher, NM Clark, MG Fernandez-Espinosa, BK Möller, D. Weijers, …
GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE 4 in Arabidopsis
How plants determine the final size of growing cells is an important, yet unresolved, issue.
Root hairs provide an excellent model system with which to study this as their final cell size is …
Root hairs provide an excellent model system with which to study this as their final cell size is …
Integration of multi‐omics data reveals interplay between brassinosteroid and Target of Rapamycin Complex signaling in Arabidopsis
Brassinosteroids (BRs) and Target of Rapamycin Complex (TORC) are two major actors
coordinating plant growth and stress responses. Brassinosteroids function through a signaling …
coordinating plant growth and stress responses. Brassinosteroids function through a signaling …