[HTML][HTML] Initial characterization of the large genome of the salamander Ambystoma mexicanum using shotgun and laser capture chromosome sequencing

MC Keinath, VA Timoshevskiy, NY Timoshevskaya… - Scientific reports, 2015 - nature.com
Vertebrates exhibit substantial diversity in genome size and some of the largest genomes
exist in species that uniquely inform diverse areas of basic and biomedical research. For …

[HTML][HTML] Germline-Specific Repetitive Elements in Programmatically Eliminated Chromosomes of the Sea Lamprey (Petromyzon marinus)

VA Timoshevskiy, NY Timoshevskaya, JJ Smith - Genes, 2019 - mdpi.com
The sea lamprey (Petromyzon marinus) is one of few vertebrate species known to reproducibly
eliminate large fractions of its genome during normal embryonic development. This …

Content of and interactions between repetitive elements in programmatically eliminated chromosomes of the sea lamprey (Petromyzon marinus)

VA Timoshevskiy, NY Timoshevskaya, JJ Smith - bioRxiv, 2019 - biorxiv.org
The sea lamprey (Petromyzon marinus) is one of few vertebrate species that is known to
reproducibly eliminate large fractions of its genome during normal embryonic development. In …

The lamprey genome: Illuminating genomic change across eons and embryogenesis

…, CB Saraceno, VA Timoshevskiy, NY Timoshevskaya - scholar.archive.org
The sea lamprey(Petromyzon marinus) is a member of an ancient vertebrate lineage that
diverged from our own lineage approximately 500 million years ago, before the evolution of …

[PDF][PDF] Supplementary Text

MC Keinath, VA Timoshevskiy, NY Timoshevskaya… - uknowledge.uky.edu
At 32 Gb, the salamander genome is~ 45% larger than the largest genomes assembled to
date (eg the 22 Gb loblolly pine genome 1). As such there are few experimental data that can …

Discovery of sex-specific regions in a salamander genome

NY Timoshevskaya, MC Keinath, JJ Smith - scholar.archive.org
Timoshevskaya NY, Keinath MC, Smith JJ. University of Kentucky, Department of Biology …

[PDF][PDF] Final Report W911NF-11-1-0475

SR Voss - Genome - apps.dtic.mil
Salamanders are important vertebrate model organisms in regenerative medicine. In this
application, we proposed to enhance research resources for the Mexican axolotl (Ambystoma …

[PDF][PDF] An improved germline genome assembly for the sea lamprey Petromyzon marinus illuminates the evolution of germline-specific chromosomes

N Timoshevskaya, Kİ Eşkut, VA Timoshevskiy… - Cell reports, 2023 - cell.com
Programmed DNA loss is a gene silencing mechanism that is employed by several
vertebrate and nonvertebrate lineages, including all living jawless vertebrates and songbirds. …

[HTML][HTML] The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution

JJ Smith, N Timoshevskaya, C Ye, C Holt, MC Keinath… - Nature …, 2018 - nature.com
The sea lamprey (Petromyzon marinus) serves as a comparative model for reconstructing
vertebrate evolution. To enable more informed analyses, we developed a new assembly of the …

A chromosome-scale assembly of the axolotl genome

JJ Smith, N Timoshevskaya, VA Timoshevskiy… - Genome …, 2019 - genome.cshlp.org
The axolotl (Ambystoma mexicanum) provides critical models for studying regeneration,
evolution, and development. However, its large genome (∼32 Gb) presents a formidable barrier …