Extracellular vesicles (EVs) are cell-derived, naturally produced, membrane-bound nanoscale
particles that are linked to cell-cell communication and the propagation of diseases. Here, …

The stress-responsive transcription factor HSF1 reduces CD8 + T-cell infiltration in breast
tumors to prevent immune-mediated killing, indicating that cellular stress responses affect …

The heat stress response activates the transcription factor heat shock factor 1 (HSF1), which
subsequently upregulates heat shock proteins to maintain the integrity of the proteome. …

In the last two decades, the zebrafish has emerged as an important model species for heart
regeneration studies. Various approaches to model loss of cardiac myocytes and myocardial …

Breast cancer is the most commonly diagnosed cancer in women and is the second leading
cause of cancer-related deaths in women. Approximately 20-30% of patients will develop …

Using cauterization of the ventricular myocardium, previous studies in our lab have shown
evidence of matrix remodeling as well as robust cardiac regeneration in the giant danio, a …

The Second International Symposium on Cellular and Organismal Stress Responses took
place virtually on September 8–9, 2022. This meeting was supported by the Cell Stress …

As chronological age of an organism increases, a number of errors accumulate at different
levels of biological organization. The tendency of errors to accumulate and cause …

The role of proteomic instability in cancer, particularly amyloidogenesis, remains obscure.
Heat shock factor 1 (HSF1) transcriptionally governs the proteotoxic stress response to …