User profiles for Natasha N. Knier

Natasha N. Knier

PhD Candidate, Western University
Verified email at uwo.ca
Cited by 109

A perspective on cell tracking with magnetic particle imaging

OC Sehl, JJ Gevaert, KP Melo, NN Knier, PJ Foster - Tomography, 2020 - mdpi.com
Many labs have been developing cellular magnetic resonance imaging (MRI), using both
superparamagnetic iron oxide nanoparticles (SPIONs) and fluorine-19 (19 F)-based cell labels…

Magnetic microspheres can be used for magnetic particle imaging of cancer cells arrested in the mouse brain

KP Melo, AV Makela, NN Knier… - Magnetic …, 2022 - Wiley Online Library
Purpose Magnetic particle imaging (MPI) is a new imaging modality that sensitively and
specifically detects superparamagnetic iron oxide nanoparticles (SPIOs). MRI cell tracking with …

[HTML][HTML] Preclinical models of brain metastases in breast cancer

NN Knier, S Pellizzari, J Zhou, PJ Foster, A Parsyan - Biomedicines, 2022 - mdpi.com
Breast cancer remains a leading cause of mortality among women worldwide. Brain metastases
confer extremely poor prognosis due to a lack of understanding of their specific biology, …

[HTML][HTML] Engineering circulating tumor cells as novel cancer theranostics

KM Parkins, VP Dubois, JJ Kelly, Y Chen, NN Knier… - Theranostics, 2020 - ncbi.nlm.nih.gov
New ways to target and treat metastatic disease are urgently needed. Tumor “self-homing”
describes the recruitment of circulating tumor cells (CTCs) back to a previously excised …

MAIT cells accumulate in ovarian cancer-elicited ascites where they retain their capacity to respond to MR1 ligands and cytokine cues

…, CM Laumont, AR Michaud, R Rashu, NN Knier… - Cancer Immunology …, 2022 - Springer
The low mutational burden of epithelial ovarian cancer (EOC) is an impediment to
immunotherapies that rely on conventional MHC-restricted, neoantigen-reactive T lymphocytes. …

Comparing the fate of brain metastatic breast cancer cells in different immune compromised mice with cellular magnetic resonance imaging

NN Knier, AM Hamilton, PJ Foster - Clinical & Experimental Metastasis, 2020 - Springer
Metastasis is the leading cause of mortality in breast cancer patients, with brain metastases
becoming increasingly prevalent. Studying this disease is challenging due to the limited …

Development of magnetic particle imaging (MPI) for cell tracking and detection

KP Melo, AV Makela, NN Knier, AM Hamilton, PJ Foster - bioRxiv, 2020 - biorxiv.org
Introduction Magnetic particle imaging (MPI) is a new imaging modality that sensitively and
specifically detects superparamagnetic iron oxide nanoparticles (SPIONs) within a sample. …

[HTML][HTML] A method for the efficient iron-labeling of patient-derived xenograft cells and cellular imaging validation

NN Knier, VP Dubois, Y Chen, JA Ronald… - Journal of Biological …, 2021 - ncbi.nlm.nih.gov
There is momentum towards implementing patient-derived xenograft models (PDX) in cancer
research to reflect the histopathology, tumor behavior, and metastatic properties observed …

Magnetic particle imaging

NN Knier, OC Sehl, JJ Gevaert, AV Makela… - Advances in Magnetic …, 2023 - Elsevier
… Author links open overlay panel Natasha N. Knier a b , Olivia C. Sehl a b , Julia J. Gevaert
a … Images from Sehl OC, Gevaert JJ, Melo KP, Knier NN, Foster PJ. A perspective on cell …

Tracking cancer cells in the mouse brain with magnetic resonance imaging (MRI) and magnetic particle imaging (MPI)

NN Knier, PJ Foster - ISMRM, 2021 - archive.ismrm.org
Magnetic particle imaging (MPI) is an emerging modality that may overcome challenges
associated with quantification of iron-based MRI cell tracking. The magnetic properties of an …