Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to
identify and quantify the peptides generated by the proteolysis of a biological sample. …

Quantitative proteomics employing mass spectrometry is an indispensable tool in life science
research. Targeted proteomics has emerged as a powerful approach for reproducible …

Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity
in the 1960s, later, the FDA classified DMSO in the safest solvent category. DMSO became …

The rigorous testing of hypotheses on suitable sample cohorts is a major limitation in translational
research. This is particularly the case for the validation of protein biomarkers; the lack …

Public repositories for proteomics data have accelerated proteomics research by enabling
more efficient cross‐analyses of datasets, supporting the creation of protein and peptide …

Targeted mass spectrometry by selected reaction monitoring (S/MRM) has proven to be a
suitable technique for the consistent and reproducible quantification of proteins across multiple …

A hot topic in recent decades, the application of organic amendments to arid-degraded soils
has been shown to benefit microbially-mediated processes. However, despite the …

Circulating levels of insulin and glucagon reflect the nutritional state of animals and elicit
regulatory responses in the liver that maintain glucose and lipid homeostasis. The transcription …

Expansion of functional islet β-cell mass is a physiological process to compensate for
increased insulin demand. Deficiency or pharmacological inhibition of the plasma membrane …

Periodontal diseases are among the most prevalent worldwide, but largely silent, chronic
diseases. They affect the tooth-supporting tissues with multiple ramifications on life quality. …