Metastasis requires the penetration of cancer cells through tight spaces, which is mediated
by the physical properties of the cells as well as their interactions with the confined …

Methods to rapidly assess cell growth would be useful for many applications, including drug
susceptibility testing, but current technologies have limited sensitivity or throughput. Here we …

We present a method for direct non-optical quantification of dry mass, dry density and water
mass of single living cells in suspension. Dry mass and dry density are obtained …

Understanding the principles that govern the assembly of microbial communities across earth's
biomes is a major challenge in modern microbial ecology. This pursuit is complicated by …

Physical characterization of nanoparticles is required for a wide range of applications.
Nanomechanical resonators can quantify the mass of individual particles with detection limits …

Simultaneously measuring multiple eigenmode frequencies of nanomechanical resonators
can determine the position and mass of surface-adsorbed proteins, and could ultimately …

We report a series of inhibitors of secreted phospholipases A 2 (sPLA 2 s) based on substituted
indoles, 6,7-benzoindoles, and indolizines derived from LY315920, a well-known indole-…

Assays that can determine the response of tumor cells to cancer therapeutics could greatly
aid the selection of drug regimens for individual patients. However, the utility of current …

Animal behaviors are commonly organized into long-lasting states that coordinately impact
the generation of diverse motor outputs such as feeding, locomotion, and grooming. However…

Circulating tumor cells (CTCs) play a fundamental role in cancer progression. However, in
mice, limited blood volume and the rarity of CTCs in the bloodstream preclude longitudinal, in-…