User profiles for Nathan R. Wilson

Nathan R. Wilson

Co-Founder and CTO, Nara Logics, Inc.
Verified email at mit.edu
Cited by 4096

[HTML][HTML] Regulation of dendritic spine morphology and synaptic function by Shank and Homer

C Sala, V Piëch, NR Wilson, M Passafaro, G Liu… - Neuron, 2001 - cell.com
The Shank family of proteins interacts with NMDA receptor and metabotropic glutamate
receptor complexes in the postsynaptic density (PSD). Targeted to the PSD by a PDZ-dependent …

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

D Tropea, E Giacometti, NR Wilson… - Proceedings of the …, 2009 - National Acad Sciences
Rett Syndrome (RTT) is a severe form of X-linked mental retardation caused by mutations in
the gene coding for methyl CpG-binding protein 2 (MECP2). Mice deficient in MeCP2 have a …

Division and subtraction by distinct cortical inhibitory networks in vivo

NR Wilson, CA Runyan, FL Wang, M Sur - Nature, 2012 - nature.com
Brain circuits process information through specialized neuronal subclasses interacting
within a network. Revealing their interplay requires activating specific cells while monitoring …

Presynaptic regulation of quantal size by the vesicular glutamate transporter VGLUT1

NR Wilson, J Kang, EV Hueske, T Leung… - Journal of …, 2005 - Soc Neuroscience
A fundamental question in synaptic physiology is whether the unitary strength of a synapse
can be regulated by presynaptic characteristics and, if so, what those characteristics might be…

[PDF][PDF] Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex

…, J Schummers, A Van Wart, SJ Kuhlman, NR Wilson… - Neuron, 2010 - cell.com
Inhibitory interneurons in the cerebral cortex include a vast array of subtypes, varying in
their molecular signatures, electrophysiological properties, and connectivity patterns. This …

Exome sequencing reveals a thrombopoietin ligand mutation in a Micronesian family with autosomal recessive aplastic anemia

…, SK Rafi, AJ Olm-Shipman, NR Wilson… - Blood, The Journal …, 2013 - ashpublications.org
We recently identified 2 siblings afflicted with idiopathic, autosomal recessive aplastic
anemia. Whole-exome sequencing identified a novel homozygous missense mutation in …

[HTML][HTML] SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination

NR Wilson, AJ Olm-Shipman, DS Acevedo… - Scientific reports, 2016 - nature.com
Cranial neural crest cells (CNCCs) delaminate from embryonic neural folds and migrate to
pharyngeal arches, which give rise to most mid-facial structures. CNCC dysfunction plays a …

Central nervous system involvement in blastic plasmacytoid dendritic cell neoplasm

N Pemmaraju, NR Wilson, JD Khoury… - Blood, The Journal …, 2021 - ashpublications.org
Nathaniel R. Wilson … Clinical profile of IMGN632, a novel CD123-targeting antibody-drug
conjugate (ADC), in patients with relapsed/refractory (R/R) blastic plasmacytoid dendritic cell …

Novel therapeutic approaches in blastic plasmacytoid dendritic cell neoplasm (BPDCN): era of targeted therapy

NR Wilson, M Konopleva, JD Khoury… - … Lymphoma Myeloma and …, 2021 - Elsevier
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
arising from the aberrant transformation of plasmacytoid dendritic cells (pDCs) and involving …