Neanderthal-Denisovan ancestors interbred with a distantly related hominin
AR Rogers, NS Harris, AA Achenbach - Science advances, 2020 - science.org
Previous research has shown that modern Eurasians interbred with their Neanderthal and
Denisovan predecessors. We show here that hundreds of thousands of years earlier, the …
Denisovan predecessors. We show here that hundreds of thousands of years earlier, the …
Genomic regions linked to soft sweeps approximate neutrality when inferring population history from site pattern frequencies
NS Harris, AR Rogers - bioRxiv, 2020 - biorxiv.org
Recent studies have suggested that selection is widespread throughout the genome and
largely uncompensated for in inferences of population history. To address this potential issue, …
largely uncompensated for in inferences of population history. To address this potential issue, …
[PDF][PDF] Neanderthal-Denisovan ancestors interbred with
AR Rogers, NS Harris, AA Achenbach - academia.edu
Previous research has shown that modern Eurasians interbred with their Ne-6 anderthal and
Denisovan predecessors. We show here that hundreds of thou-7 sands of years earlier, the …
Denisovan predecessors. We show here that hundreds of thou-7 sands of years earlier, the …
Sharing of weak signals of positive selection across the genome
NS Harris, AR Rogers - bioRxiv, 2020 - biorxiv.org
Selection in humans often leaves subtle signatures at individual loci. Few studies have
measured the extent to which these signals are shared among human populations. Here a new …
measured the extent to which these signals are shared among human populations. Here a new …
Detecting shared independent selection
NS Harris, AR Rogers - bioRxiv, 2020 - biorxiv.org
Signals of selection are not often shared between populations. When a mutual signal is
detected, it is often not known if selection occurred before or after populations split. Here we …
detected, it is often not known if selection occurred before or after populations split. Here we …
Shared Selection and Population History
NS Harris - 2020 - search.proquest.com
Natural selection and population history both leave signatures in the genomes of populations.
Disentangling these effects is essential to their study. I approach this problem in three …
Disentangling these effects is essential to their study. I approach this problem in three …
Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney
Elevated blood pressure is a major risk factor for cardiovascular disease and has a substantial
genetic contribution. Genetic variation influencing blood pressure has the potential to …
genetic contribution. Genetic variation influencing blood pressure has the potential to …
Extensive somatic L1 retrotransposition in colorectal tumors
L1 retrotransposons comprise 17% of the human genome and are its only autonomous mobile
elements. Although L1-induced insertional mutagenesis causes Mendelian disease, their …
elements. Although L1-induced insertional mutagenesis causes Mendelian disease, their …
The APOBEC3 family of retroelement restriction factors
EW Refsland, RS Harris - Intrinsic immunity, 2013 - Springer
The ability to regulate and even target mutagenesis is an extremely valuable cellular asset.
Enzyme-catalyzed DNA cytosine deamination is a molecular strategy employed by …
Enzyme-catalyzed DNA cytosine deamination is a molecular strategy employed by …
Health service staff attitudes to community representatives on committees
The paper finds that significantly more staff at the follow‐up survey reported that they and
other staff were clear about the role of community representatives and how to work with them …
other staff were clear about the role of community representatives and how to work with them …