Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism
…, MJ Temple, Y Zhu, EA Cameron, NA Pudlo, NT Porter… - Nature, 2015 - nature.com
Yeasts, which have been a component of the human diet for at least 7,000 years, possess an
elaborate cell wall α-mannan. The influence of yeast mannan on the ecology of the human …
elaborate cell wall α-mannan. The influence of yeast mannan on the ecology of the human …
The critical roles of polysaccharides in gut microbial ecology and physiology
NT Porter, EC Martens - Annual review of microbiology, 2017 - annualreviews.org
The human intestine harbors a dense microbial ecosystem (microbiota) that is different
between individuals, dynamic over time, and critical for aspects of health and disease. Dietary …
between individuals, dynamic over time, and critical for aspects of health and disease. Dietary …
Phase-variable capsular polysaccharides and lipoproteins modify bacteriophage susceptibility in Bacteroides thetaiotaomicron
NT Porter, AJ Hryckowian, BD Merrill, JJ Fuentes… - Nature …, 2020 - nature.com
A variety of cell surface structures dictate interactions between bacteria and their environment,
including their viruses (bacteriophages). Members of the human gut Bacteroidetes …
including their viruses (bacteriophages). Members of the human gut Bacteroidetes …
[PDF][PDF] Colitogenic Bacteroides thetaiotaomicron antigens access host immune cells in a sulfatase-dependent manner via outer membrane vesicles
CA Hickey, KA Kuhn, DL Donermeyer, NT Porter… - Cell host & …, 2015 - cell.com
Microbes interact with the host immune system via several potential mechanisms. One
essential step for each mechanism is the method by which intestinal microbes or their antigens …
essential step for each mechanism is the method by which intestinal microbes or their antigens …
Investigation and alteration of organic acid synthesis pathways in the mammalian gut symbiont Bacteroides thetaiotaomicron
NT Porter, J Larsbrink - Microbiology Spectrum, 2022 - Am Soc Microbiol
Members of the gut-dwelling Bacteroides genus have remarkable abilities in degrading a
diverse set of fiber polysaccharide structures, most of which are found in the mammalian diet. …
diverse set of fiber polysaccharide structures, most of which are found in the mammalian diet. …
Reciprocal prioritization to dietary glycans by gut bacteria in a competitive environment promotes stable coexistence
When presented with nutrient mixtures, several human gut Bacteroides species exhibit
hierarchical utilization of glycans through a phenomenon that resembles catabolite repression. …
hierarchical utilization of glycans through a phenomenon that resembles catabolite repression. …
[PDF][PDF] A subset of polysaccharide capsules in the human symbiont Bacteroides thetaiotaomicron promote increased competitive fitness in the mouse gut
Capsular polysaccharides (CPSs) play multiple roles in protecting bacteria from host and
environmental factors, and many commensal bacteria can produce multiple capsule types. To …
environmental factors, and many commensal bacteria can produce multiple capsule types. To …
Bacteroides thetaiotaomicron
NT Porter, AS Luis, EC Martens - Trends in microbiology, 2018 - cell.com
This infographic on Bacteroides thetaiotaomicron (Bt) explores the ability of this microbe to
digest a broad array of complex carbohydrates, alter its surface features, and its emerging …
digest a broad array of complex carbohydrates, alter its surface features, and its emerging …
[PDF][PDF] Bacteroides thetaiotaomicron-infecting bacteriophage isolates inform sequence-based host range predictions
Our emerging view of the gut microbiome largely focuses on bacteria, while less is known
about other microbial components, such as bacteriophages (phages). Though phages are …
about other microbial components, such as bacteriophages (phages). Though phages are …
Polysaccharide capsules equip the human symbiont Bacteroides thetaiotaomicron to modulate immune responses to a dominant antigen in the intestine
S Hsieh, NT Porter, DL Donermeyer… - The Journal of …, 2020 - journals.aai.org
Bacteria express multiple diverse capsular polysaccharides (CPSs) for protection against
environmental and host factors, including the host immune system. Using a mouse TCR …
environmental and host factors, including the host immune system. Using a mouse TCR …