[PDF][PDF] Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters
SARS-CoV-2 infection results in viral burden in the respiratory tract, enabling transmission
and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody was …
and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody was …
Circulating SARS-CoV-2+ megakaryocytes are associated with severe viral infection in COVID-19
…, F Huls, R Chkheidze, P Li, NB Erdmann… - Blood …, 2023 - ashpublications.org
Several independent lines of evidence suggest that megakaryocytes are dysfunctional in
severe COVID-19. Herein, we characterized peripheral circulating megakaryocytes in a large …
severe COVID-19. Herein, we characterized peripheral circulating megakaryocytes in a large …
[HTML][HTML] Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing …
…, D Chauvin, J Woo, P Lovalenti, NB Erdmann… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) marks the third novel β-coronavirus
to cause significant human mortality in the last two decades. Although vaccines …
to cause significant human mortality in the last two decades. Although vaccines …
[HTML][HTML] Interferon-dependent signaling is critical for viral clearance in airway neutrophils
…, MC Madison, SM Leal Jr, KS Harrod, NB Erdmann… - JCI insight, 2023 - ncbi.nlm.nih.gov
Neutrophilic inflammation characterizes several respiratory viral infections, including COVID-19–related
acute respiratory distress syndrome, although its contribution to disease …
acute respiratory distress syndrome, although its contribution to disease …
[HTML][HTML] Nicotinamide adenine dinucleotide biosynthetic impairment and urinary metabolomic alterations observed in hospitalized adults with COVID-19–related acute …
…, LS Wilson, JC Edberg, NB Erdmann… - Kidney International …, 2021 - Elsevier
Introduction Acute kidney injury (AKI) is common in COVID-19 and associated with increased
morbidity and mortality. We investigated alterations in the urine metabolome to test the …
morbidity and mortality. We investigated alterations in the urine metabolome to test the …
[HTML][HTML] Single-cell RNA sequencing of urinary cells reveals distinct cellular diversity in COVID-19–associated AKI
MD Cheung, EN Erman, S Liu, NB Erdmann… - Kidney360, 2022 - journals.lww.com
Background AKI is a common sequela of infection with SARS-CoV-2 and contributes to the
severity and mortality from COVID-19. Here, we tested the hypothesis that kidney alterations …
severity and mortality from COVID-19. Here, we tested the hypothesis that kidney alterations …
[HTML][HTML] Herpes zoster in persons living with HIV-1 infection: viremia and immunological defects are strong risk factors in the era of combination antiretroviral therapy
NB Erdmann, HA Prentice, A Bansal… - Frontiers in Public …, 2018 - frontiersin.org
In a cohort of 4,225 persons living with human immunodeficiency virus type 1 (HIV-1) infection
(PLWH) enrolled at a southeastern US clinic, the overall rate of incident herpes zoster (HZ…
(PLWH) enrolled at a southeastern US clinic, the overall rate of incident herpes zoster (HZ…
Potent universal-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody
…, S Sarkar, D Chauvin, J Woo, P Lovalenti, NB Erdmann… - bioRxiv, 2022 - biorxiv.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) marks the third novel β-coronavirus
to cause significant human mortality in the last two decades. Although vaccines …
to cause significant human mortality in the last two decades. Although vaccines …
[HTML][HTML] Type I interferon-dependent IFIT3 signaling is critical for viral clearance in airway neutrophils
…, SM Leal Jr, KS Harrod, NB Erdmann… - Research …, 2023 - ncbi.nlm.nih.gov
Neutrophilic inflammation characterizes several respiratory viral infections including COVID-19-related
ARDS, although its contribution to disease pathogenesis remains poorly …
ARDS, although its contribution to disease pathogenesis remains poorly …
[HTML][HTML] COVID-19 Vaccination and Remdesivir are Associated With Protection From New or Increased Levels of Donor-Specific Antibodies Among Kidney Transplant …
…, AC Killian, SC Ong, NB Erdmann… - Transplant …, 2022 - frontierspartnerships.org
Alloimmune responses in kidney transplant (KT) patients previously hospitalized with COVID-19
are understudied. We analyzed a cohort of 112 kidney transplant recipients who were …
are understudied. We analyzed a cohort of 112 kidney transplant recipients who were …