[HTML][HTML] Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling
Single-cell RNA-seq is a powerful tool in decoding the heterogeneity in complex tissues by
generating transcriptomic profiles of the individual cell. Here, we report a single-nuclei RNA-…
generating transcriptomic profiles of the individual cell. Here, we report a single-nuclei RNA-…
Photochromic Benzo[b]phosphole Alkynylgold(I) Complexes with Mechanochromic Property to Serve as Multistimuli‐Responsive Materials
A series of novel benzo[b]phosphole alkynylgold(I) complexes has been demonstrated to
display photochromic and mechanochromic properties upon applying the respective stimuli of …
display photochromic and mechanochromic properties upon applying the respective stimuli of …
Oral-recombinant methioninase converts an osteosarcoma from docetaxel-resistant to-sensitive in a clinically-relevant patient-derived orthotopic-xenograft (PDOX) …
Y Aoki, Y Tome, NF Wu, J Yamamoto… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Osteosarcoma is the most frequent malignant bone tumor. Failure of first-line
therapy results in poor prognosis of osteosarcoma. In the present report, we examined the …
therapy results in poor prognosis of osteosarcoma. In the present report, we examined the …
Oral-recombinant methioninase in combination with rapamycin eradicates osteosarcoma of the breast in a patient-derived orthotopic xenograft mouse model
…, Q Han, C Samonte, NF Wu, C Hozumi, J Wu… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Primary osteosarcoma of the breast is a very rare malignancy that shares
histological features with osteosarcoma. It is also highly sensitive to methionine restriction …
histological features with osteosarcoma. It is also highly sensitive to methionine restriction …
Oral-recombinant methioninase lowers the effective dose and eliminates toxicity of cisplatinum for primary osteosarcoma of the mammary gland in a patient-derived …
N Masaki, Q Han, NF Wu, C Samonte, J Wu, C Hozumi… - in vivo, 2022 - iv.iiarjournals.org
Background/Aim: Primary osteosarcoma of the mammary gland is a very rare disease,
accounting for under 1% of all mammary gland malignancies. There is no established first-line …
accounting for under 1% of all mammary gland malignancies. There is no established first-line …
The first mouse model of primary osteosarcoma of the breast
NF Wu, J Wu, J Yamamoto, Y Aoki, C Hozumi… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: Sarcomas of the breast are extremely rare malignant tumors and comprise
only 5% of all sarcomas and fewer than 1% of breast cancers. Primary osteosarcoma of the …
only 5% of all sarcomas and fewer than 1% of breast cancers. Primary osteosarcoma of the …
Transcript isoforms of Reep6 have distinct functions in the retina
Q Liang, N Wu, S Zaneveld, H Liu, S Fu… - Human Molecular …, 2021 - academic.oup.com
Much of the complexity of the eukaryotic cell transcriptome is due to the alternative splicing
of mRNA. However, knowledge on how transcriptome complexity is translated into functional …
of mRNA. However, knowledge on how transcriptome complexity is translated into functional …
The application of nanotechnology for quantification of circulating tumour DNA in liquid biopsies: a systematic review
Technologies for quantifying circulating tumour DNA (ctDNA) in liquid biopsies could
enable real-time measurements of cancer progression, profoundly impacting patient care. …
enable real-time measurements of cancer progression, profoundly impacting patient care. …
Oxepine-Based π-Conjugated Ladder/Step-Ladder Polymers with Excited-State Aromaticity
NMW Wu, MC Warndorf, A Alexander-Katz… - …, 2024 - ACS Publications
Ladder polymers with backbones of uninterrupted ring-fused units have attracted academic
and industrial attention for decades because of their extended π-conjugation and intrinsic …
and industrial attention for decades because of their extended π-conjugation and intrinsic …
Benzo[b]Germole-Fused Diarylethenes as Photochromic Organogermanium Compounds
The molecular design of various heterocycles incorporated into photochromic diarylethenes
plays an important role in diversifying functionality. Herein, we report the design, synthesis, …
plays an important role in diversifying functionality. Herein, we report the design, synthesis, …