Stimulating regeneration of complex tissues and organs after injury to effect complete structural
and functional repair, is an attractive therapeutic option that would revolutionize clinical …

Thyroid hormone is a critical regulator of cardiac growth and development, both in fetal life
and postnatally. Here we review the role of thyroid hormone in postnatal cardiac development…

It is widely believed that perinatal cardiomyocyte terminal differentiation blocks cytokinesis,
thereby causing binucleation and limiting regenerative repair after injury. This suggests that …

Ang I–converting enzyme (ACE) inhibitors are widely believed to suppress the deleterious
cardiac effects of Ang II by inhibiting locally generated Ang II. However, the recent …

Uremic cardiomyopathy and muscle atrophy are associated with insulin resistance and
contribute to chronic kidney disease (CKD)-induced morbidity and mortality. We hypothesized …

Purpose Intimal hyperplasia (IH), a well-recognized cause of dialysis vascular access failure,
is generally believed to be an acquired pathologic lesion. Recent data suggests that IH is …

Macrophages are an essential component of the immune response to ischaemic injury and
play an important role in promoting inflammation and its resolution, which is necessary for …

Recent data indicates that DJ-1 plays a role in the cellular response to stress. Here, we
aimed to examine the underlying molecular mechanisms mediating the actions of DJ-1 in the …

Background— Therapeutic strategies aimed at increasing hydrogen sulfide (H 2 S) levels
exert cytoprotective effects in various models of cardiovascular injury. However, the underlying …

Background Lymphatic vessels interconnect with blood vessels to form an elaborate system
that aids in the control of tissue pressure and edema formation. Although the lymphatic …