[HTML][HTML] Anatomy and behavioral function of serotonin receptors in Drosophila melanogaster larvae

A Huser, M Eschment, N Güllü, KAN Collins, K Böpple… - PloS one, 2017 - journals.plos.org
The biogenic amine serotonin (5-HT) is an important neuroactive molecule in the central
nervous system of the majority of animal phyla. 5-HT binds to specific G protein-coupled and …

[HTML][HTML] Insulin signaling represents a gating mechanism between different memory phases in Drosophila larvae

M Eschment, HR Franz, N Güllü, LG Hölscher… - PloS …, 2020 - journals.plos.org
The ability to learn new skills and to store them as memory entities is one of the most
impressive features of higher evolved organisms. However, not all memories are created equal; …

[HTML][HTML] MACC1-dependent antitumor effect of curcumin in colorectal cancer

N Güllü, J Smith, P Herrmann, U Stein - Nutrients, 2022 - mdpi.com
Metastasis is the main reason for the high mortality rate of colorectal cancer (CRC) patients.
Despite the whole improvement in the field of cancer medicine, the treatment options for the …

[HTML][HTML] Saffron crudes and compounds restrict MACC1-dependent cell proliferation and migration of colorectal cancer cells

N Güllü, D Kobelt, H Brim, S Rahman, L Timm, J Smith… - Cells, 2020 - mdpi.com
The high mortality rate of colorectal cancer (CRC) patients is directly associated with metastatic
dissemination. However, therapeutic options specifically for metastasis are still limited. …

[HTML][HTML] Small Ones to Fight a Big Problem—Intervention of Cancer Metastasis by Small Molecules

D Kobelt, M Dahlmann, M Dumbani, N Güllü, B Kortüm… - Cancers, 2020 - mdpi.com
Metastasis represents the most lethal attribute of cancer and critically limits successful
therapies in many tumor entities. The clinical need is defined by the fact that all cancer patients, …

Saffron restricts MACC1-dependent cell proliferation and motility of colorectal cancer cells, and alters the microbiome structure

N Güllü, D Kobelt, H Brim, L Timm, J Smith, H Shoraka… - Cancer Research, 2019 - AACR
Saffron has proven a beneficial effect as a supplement in the treatment of many conditions
through its perceived anti-oxidative and anti-inflammatory properties. We previously identified …

Insulin signaling gates long-term memory formation in Drosophila larvae

M Eschment, HR Franz, N Güllü, LG Hölscher, KE Huh… - bioRxiv, 2019 - biorxiv.org
The ability to learn new skills and to store them as memory entities is one of the most
impressive features of higher evolved organisms. However, not all memories are created equal; …

Abstract B045: The effect of metastasis-associated in colon cancer 1 (MACC1) on therapy-induced senescence and its impact on post-senescence-driven metastasis

BN Güllü, DNY Fan, D Kobelt, M Mokrizkij, J Smith… - Cancer Research, 2023 - AACR
Senescence is considered a safeguard program against cancer progression. However, recent
studies revealed that these cells, reprogrammed in a senescence-associated fashion to …

Effect of axial ligand length on biological and anticancer properties of axially disubstituted silicon phthalocyanines

…, D Bahar, S Özdemir, G Tollu, M Güllü… - Chemistry & …, 2023 - Wiley Online Library
In this study, three new axially disubstituted silicon phthalocyanines (SiPc1–3) and their
quaternized phthalocyanine derivatives (QSiPc1–3) were prepared and characterized. The …

Selmân-ı Sâvecî'nin Gül Redifli Gazelinde Gülün Ele Alınışı

Y YAYLALI - Atatürk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2018 - dergipark.org.tr
… Birinci mısrada gülfidanının yani gülün yeşermesi narinlik açısından ve ikinci mısrada da “nazlı
endamı” nitelemesiyle vasf edilerek güzellere teşbih edilen gülün tüm bu narinliğine ve …