Homozygosity mapping is a powerful method for identifying mutations in patients with recessive
conditions, especially in consanguineous families or isolated populations. Historically, it …

Colorectal cancer (CRC) is one of the major causes of cancer deaths across the world.
Patients’ survival at time of diagnosis depends mainly on stage of the tumor. Therefore, …

Objective Male infertility is a multifactorial disease resulting from the interaction between the
genetic and environmental factors. Spermatogenic failure accounts for more than half of …

microRNAs (miRNAs) are negative regulators in a variety of cellular processes that occur in
endometriosis. Therefore, functional polymorphisms in miRNA and miRNA binding sites may …

Inherited retinal dystrophies (IRDs) constitute one of the most heterogeneous groups of
Mendelian human disorders. Using autozygome-guided next-generation sequencing methods in …

Visceral leishmaniosis (VL) is one of the neglected tropical diseases despite being responsible
for serious clinical symptoms, some of which lead to fatal outcomes. Thus, there is a …

Colorectal cancer is one of the leading causes of cancer death worldwide. Patients’ survival
at the time of diagnosis depends largely on the stage of the tumor. Therefore, understanding …

Loop-mediated isothermal amplification (LAMP) does not require thermal cycler machines
to amplify DNA and has the potential to revolutionize molecular biology by bypassing the …

In recent years the volume of biological data has soared. Parallel to this growth, the need for
developing data mining strategies has not met sufficiently. Here we applied data mining …

Cellular redox homeostasis is the important tool for normal cell function and survival. Oxidants,
reductants and antioxidants are the players to maintain cellular homeostasis balance. …