[HTML][HTML] Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
Background System-wide profiling of genes and proteins in mammalian cells produce lists
of differentially expressed genes/proteins that need to be further analyzed for their collective …
of differentially expressed genes/proteins that need to be further analyzed for their collective …
[HTML][HTML] L1000CDS2: LINCS L1000 characteristic direction signatures search engine
The library of integrated network-based cellular signatures (LINCS) L1000 data set currently
comprises of over a million gene expression profiles of chemically perturbed human cell …
comprises of over a million gene expression profiles of chemically perturbed human cell …
[PDF][PDF] Induction of a hemogenic program in mouse fibroblasts
…, J Qiu, X Niu, D Papatsenko, CE Hendry, NR Clark… - Cell stem cell, 2013 - cell.com
Definitive hematopoiesis emerges during embryogenesis via an endothelial-to-hematopoietic
transition. We attempted to induce this process in mouse fibroblasts by screening a panel …
transition. We attempted to induce this process in mouse fibroblasts by screening a panel …
[HTML][HTML] Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
…, KS Hu, MG McDermott, Q Duan, NR Clark… - Nature …, 2016 - nature.com
Gene expression data are accumulating exponentially in public repositories. Reanalysis and
integration of themed collections from these studies may provide new insights, but requires …
integration of themed collections from these studies may provide new insights, but requires …
Intramural myocardial shortening in hypertensive left ventricular hypertrophy with normal pump function.
LC Palmon, N Reichek, SB Yeon, NR Clark… - Circulation, 1994 - Am Heart Assoc
BACKGROUND In hypertensive left ventricular hypertrophy (LVH), intrinsic myocardial systolic
function may be normal or depressed. Magnetic resonance tagging can depict intramural …
function may be normal or depressed. Magnetic resonance tagging can depict intramural …
[HTML][HTML] The characteristic direction: a geometrical approach to identify differentially expressed genes
NR Clark, KS Hu, AS Feldmann, Y Kou, EY Chen… - BMC …, 2014 - Springer
Background Identifying differentially expressed genes (DEG) is a fundamental step in studies
that perform genome wide expression profiling. Typically, DEG are identified by univariate …
that perform genome wide expression profiling. Typically, DEG are identified by univariate …
Drug-induced adverse events prediction with the LINCS L1000 data
Motivation: Adverse drug reactions (ADRs) are a central consideration during drug development.
Here we present a machine learning classifier to prioritize ADRs for approved drugs …
Here we present a machine learning classifier to prioritize ADRs for approved drugs …
Circumferential myocardial shortening in the normal human left ventricle. Assessment by magnetic resonance imaging using spatial modulation of magnetization.
NR Clark, N Reichek, P Bergey, EA Hoffman… - Circulation, 1991 - Am Heart Assoc
BACKGROUND Conventional cardiac imaging methods do not depict true segmental
myocardial shortening, since they cannot determine segment length between fixed points in the …
myocardial shortening, since they cannot determine segment length between fixed points in the …
A review of past research on dendrometers
NA Clark, RH Wynne, DL Schmoldt - Forest Science, 2000 - academic.oup.com
The purpose of a dendrometer is to measure tree diameter. Contact and noncontact
dendrometers accomplish this task by collecting different metrics, including girth or distance …
dendrometers accomplish this task by collecting different metrics, including girth or distance …
Inflammation, stress and depression: an exploration of ketamine's therapeutic profile
…, ID Henter, C Kraus, A Mkrtchian, NG Clark… - Drug Discovery …, 2023 - Elsevier
Highlights • Chronic stress, depression and inflammation have been consistently linked. •
Stress-induced inflammatory states can contribute to treatment resistance. • Ketamine could be …
Stress-induced inflammatory states can contribute to treatment resistance. • Ketamine could be …