[HTML][HTML] Rapid identification of pathogenic bacteria using Raman spectroscopy and deep learning

…, L Blackmon, SS Jeffrey, M Holodniy, N Banaei… - Nature …, 2019 - nature.com
Raman optical spectroscopy promises label-free bacterial detection, identification, and antibiotic
susceptibility testing in a single step. However, achieving clinically relevant speeds and …

New and developing diagnostic technologies for urinary tract infections

…, KE Mach, LMD Shortliffe, N Banaei… - Nature Reviews …, 2017 - nature.com
Timely and accurate identification and determination of the antimicrobial susceptibility of
uropathogens is central to the management of UTIs. Urine dipsticks are fast and amenable to …

Gamma interferon release assays for detection of Mycobacterium tuberculosis infection

…, DW Dowdy, K Dheda, N Banaei - Clinical microbiology …, 2014 - Am Soc Microbiol
Identification and treatment of latent tuberculosis infection (LTBI) can substantially reduce
the risk of developing active disease. However, there is no diagnostic gold standard for LTBI. …

Clinical impact of metagenomic next-generation sequencing of plasma cell-free DNA for the diagnosis of infectious diseases: a multicenter retrospective cohort study

…, J Dien Bard, BA Pinsky, N Banaei - Clinical Infectious …, 2021 - academic.oup.com
Background Metagenomic next-generation sequencing (mNGS) of plasma cell-free DNA
has emerged as an attractive diagnostic modality allowing broad-range pathogen detection, …

Electric field-driven microfluidics for rapid CRISPR-based diagnostics and its application to detection of SARS-CoV-2

…, MK Sahoo, CH Huang, N Banaei… - Proceedings of the …, 2020 - National Acad Sciences
The rapid spread of COVID-19 across the world has revealed major gaps in our ability to
respond to new virulent pathogens. Rapid, accurate, and easily configurable molecular …

[HTML][HTML] The immunoregulatory landscape of human tuberculosis granulomas

…, D Kalman, D Kaushal, RL Hunter, N Banaei… - Nature …, 2022 - nature.com
Tuberculosis (TB) in humans is characterized by formation of immune-rich granulomas in
infected tissues, the architecture and composition of which are thought to affect disease …

Challenges and pitfalls of morphologic identification of fungal infections in histologic and cytologic specimens: a ten-year retrospective review at a single institution

…, JG Montoya, EJ Baron, N Banaei - American journal of …, 2009 - academic.oup.com
Despite the advantages of providing an early presumptive diagnosis, fungal classification by
histopathology can be difficult and may lead to diagnostic error. To assess the accuracy of …

Interferon-γ release assay for accurate detection of severe acute respiratory syndrome coronavirus 2 T-cell response

…, A Sette, BA Pinsky, U Singh, N Banaei - Clinical Infectious …, 2021 - academic.oup.com
We investigated feasibility and accuracy of an interferon-γ release assay (IGRA) for
detection of T-cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). …

Clinical application and limitations of interferon-γ release assays for the diagnosis of latent tuberculosis infection

…, S Perry, J Parsonnet, N Banaei - Clinical infectious …, 2011 - academic.oup.com
Interferon-release assays (IGRAs) represent advances in tuberculosis immunology and
evolutionary biology. IGRAs were designed to replace tuberculin skin test (TST) for the diagnosis …

[HTML][HTML] Next-generation sequencing for infectious disease diagnosis and management: a report of the Association for Molecular Pathology

MI Lefterova, CJ Suarez, N Banaei… - The Journal of Molecular …, 2015 - Elsevier
Next-generation sequencing (NGS) technologies are increasingly being used for diagnosis
and monitoring of infectious diseases. Herein, we review the application of NGS in clinical …