[HTML][HTML] Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission

…, GM Savva, R Myers, E Volz, N Ellaby… - Nature …, 2022 - nature.com
Mitigation of SARS-CoV-2 transmission from international travel is a priority. We evaluated
the effectiveness of travellers being required to quarantine for 14-days on return to England in …

The origins and molecular evolution of SARS-CoV-2 lineage B. 1.1. 7 in the UK

…, R Colquhoun, AM Carabelli, N Ellaby… - Virus …, 2022 - academic.oup.com
The first SARS-CoV-2 variant of concern (VOC) to be designated was lineage B.1.1.7, later
labelled by the World Health Organization as Alpha. Originating in early autumn but …

[HTML][HTML] Emergence of diversity in carbapenemase-producing Escherichia coli ST131, England, January 2014 to June 2016

N Ellaby, M Doumith, KL Hopkins… - …, 2019 - eurosurveillance.org
Nicholas Ellaby conducted all bioinformatic and statistical analysis on this project, and
was … =Nicholas+Ellaby&option1=author&noRedirect=true" class="nonDisambigAuthorLink">…

[HTML][HTML] Oral iron exacerbates colitis and influences the intestinal microbiome

A Mahalhal, JM Williams, S Johnson, N Ellaby… - PLoS …, 2018 - journals.plos.org
Inflammatory bowel disease (IBD) is associated with anaemia and oral iron replacement to
correct this can be problematic, intensifying inflammation and tissue damage. The intestinal …

[PDF][PDF] Detection in livestock of the human pandemic Escherichia coli ST131 fimH30(R) clone carrying blaCTX-M-27

…, MJ Ellington, KL Hopkins, N Ellaby… - Journal of …, 2021 - academic.oup.com
Sir, ESBL-producing MDR Escherichia coli ST131 is associated with a global pandemic,
causing extra-intestinal human infections that can be fatal, and is considered to be more …

[HTML][HTML] Generation of SARS-CoV-2 escape mutations by monoclonal antibody therapy

…, M Selvaraj, N Groves, H Hartman, N Ellaby… - Nature …, 2023 - nature.com
COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal
antibodies (mAbs). To minimise virus escape from neutralisation these are administered as …

An integrated analysis of contact tracing and genomics to assess the efficacy of travel restrictions on SARS-CoV-2 introduction and transmission in England from June …

…, U Schaefer, GM Savva, R Myers, E Volz, N Ellaby… - MedRxiv, 2021 - medrxiv.org
Background Mitigation of SARS-CoV-2 transmission from international travel is a priority.
Travellers from countries with travel restrictions (closed travel-corridors) were required to …

Selection and characterization of mutational resistance to aztreonam/avibactam in β-lactamase-producing Enterobacterales

S Mushtaq, A Vickers, N Ellaby… - Journal of …, 2022 - academic.oup.com
Background Aztreonam/avibactam is being developed for its broad activity against
carbapenemase-producing Enterobacterales, including those with metallo-β-lactamases (MBLs). Its …

Diversity of carbapenemase-producing Enterobacterales in England as revealed by whole-genome sequencing of isolates referred to a national reference laboratory …

KL Hopkins, N Ellaby, MJ Ellington… - Journal of Medical …, 2022 - microbiologyresearch.org
Introduction. Increasing numbers of carbapenemase-producing Enterobacterales (CPE),
which can be challenging to treat, have been referred to the national reference laboratory in …

NDM-1 carbapenemase resistance gene vehicles emergent on distinct plasmid backbones from the IncL/M family

M Lopez-Diaz, N Ellaby, J Turton… - Journal of …, 2022 - academic.oup.com
Objectives To assess the genetic contexts surrounding bla NDM-1 genes carried on IncM
plasmids harboured by six carbapenemase-producing Enterobacterales (CPE) isolates …