User profiles for Nicholas J. Justice

Nicholas Justice

Institute of Molecular Medicine, UT Houston
Verified email at uth.tmc.edu
Cited by 4411

Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation

…, MA Staup, AR Lee, NJ Justice… - Proceedings of the …, 2012 - National Acad Sciences
Exposure and/or sensitivity to stress have been implicated as conferring risk for development
of Alzheimer's disease (AD). Although the basis for such a link remains unclear, we …

Parvalbumin+ neurons and Npas1+ neurons are distinct neuron classes in the mouse external globus pallidus

…, KE Glajch, JE Pitt, TY Huang, NJ Justice… - Journal of …, 2015 - Soc Neuroscience
Compelling evidence suggests that pathological activity of the external globus pallidus (GPe),
a nucleus in the basal ganglia, contributes to the motor symptoms of a variety of movement …

[HTML][HTML] CRF signaling between neurons in the paraventricular nucleus of the hypothalamus (PVN) coordinates stress responses

Z Jiang, S Rajamanickam, NJ Justice - Neurobiology of stress, 2019 - Elsevier
The importance of a precisely coordinated neuroendocrine, autonomic, and behavioral
stress response was a primary theme at the Stress Neurobiology Workshop 2018, held in the …

Npas1+-Nkx2. 1+ neurons are an integral part of the cortico-pallido-cortical loop

…, U Chon, BK Lim, Y Kim, NJ Justice… - Journal of …, 2020 - Soc Neuroscience
Within the basal ganglia circuit, the external globus pallidus (GPe) is critically involved in motor
control. Aside from Foxp2 + neurons and ChAT + neurons that have been established as …

[HTML][HTML] The relationship between stress and Alzheimer's disease

NJ Justice - Neurobiology of stress, 2018 - Elsevier
Stress is critically involved in the development and progression of disease. From the stress of
undergoing treatments to facing your own mortality, the physiological processes that stress …

Type 1 corticotropin‐releasing factor receptor expression reported in BAC transgenic mice: implications for reconciling ligand‐receptor mismatch in the central …

NJ Justice, ZF Yuan, PE Sawchenko… - Journal of Comparative …, 2008 - Wiley Online Library
In addition to its established role in initiating the endocrine arm of the stress response,
corticotropin‐releasing factor (CRF) can act in the brain to modulate neural pathways that effect …

GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor β signaling and enhance cell growth

G Shani, WH Fischer, NJ Justice, JA Kelber… - … and cellular biology, 2008 - Taylor & Francis
Cripto is a multifunctional cell surface protein with important roles in vertebrate embryogenesis
and the progression of human tumors. While Cripto has been shown to modulate multiple …

Local corticotropin-releasing factor signaling in the hypothalamic paraventricular nucleus

Z Jiang, S Rajamanickam, NJ Justice - Journal of Neuroscience, 2018 - Soc Neuroscience
Corticotropin-releasing factor (CRF) neurons in the hypothalamic paraventricular nucleus (PVN)
initiate hypothalamic–pituitary–adrenal axis activity through the release of CRF into the …

[PDF][PDF] Asynchronous onset of odorant receptor expression in the developing zebrafish olfactory system

AL Barth, NJ Justice, J Ngai - Neuron, 1996 - cell.com
The functional identity of an olfactory neuron is determined in large part by the odorant
receptors it expresses. As an approach toward understanding the events that underlie the …

Amyloid precursor protein regulates Cav1. 2 L-type calcium channel levels and function to influence GABAergic short-term plasticity

L Yang, Z Wang, B Wang, NJ Justice… - Journal of …, 2009 - Soc Neuroscience
Amyloid precursor protein (APP) has been strongly implicated in the pathogenesis of
Alzheimer's disease (AD). Although impaired synaptic function is believed to be an early and …