A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi
and plants are known to be encoded in biosynthetic gene clusters. Information about these …

Genomics and metabolomics are widely used to explore specialized metabolite diversity.
The Paired Omics Data Platform is a community initiative to systematically document links …

Xenorhabdus and Photorhabdus species dedicate a large amount of resources to the
production of specialized metabolites derived from non-ribosomal peptide synthetase (NRPS) or …

Bacterial pigments of the aryl polyene type are structurally similar to the well‐known carotenoids
with respect to their polyene systems. Their biosynthetic gene cluster is widespread in …

Microorganisms contribute to the biology and physiology of eukaryotic hosts and affect other
organisms through natural products. Xenorhabdus and Photorhabdus (XP) living in …

Members of the genera Xenorhabdus and Photorhabdus are capable of producing a huge
repertoire of different natural products to support a complex life cycle involving insect …

Photorhabdus luminescens maintains a symbiotic relationship with the nematodes
Heterorhabditis bacteriophora and together they infect and kill insect larvae. To maintain this …

Aryl polyene (APE) pigments are a widely distributed class of bacterial polyketides. So far,
little is known about the biosynthesis of these compounds, which are produced by a novel …

Quorum sensing (QS) is widely accepted as a procedure that bacteria use to converse.
However, prevailing thinking places acyl homoserine lactones (AHLs) at the forefront of this …

Background In this report we have explored the genomic and microbiological basis for a
sustained increase in bloodstream infections at a major Australian hospital caused by …