User profiles for Nicholas MacKnight

Nicholas MacKnight

Postdoctoral Associate, University of Miami | Research Affiliate, NOAA AOML
Verified email at noaa.gov
Cited by 137

[HTML][HTML] Stony coral tissue loss disease induces transcriptional signatures of in situ degradation of dysfunctional Symbiodiniaceae

…, AJ Veglia, CE Karrick, NJ MacKnight… - Nature …, 2023 - nature.com
Stony coral tissue loss disease (SCTLD), one of the most pervasive and virulent coral
diseases on record, affects over 22 species of reef-building coral and is decimating reefs …

[HTML][HTML] Variable species responses to experimental stony coral tissue loss disease (SCTLD) exposure

…, A Rossin, AJ Veglia, N MacKnight… - Frontiers in Marine …, 2021 - frontiersin.org
Stony coral tissue loss disease (SCTLD) was initially documented in Florida in 2014 and
outbreaks with similar characteristics have since appeared in disparate areas throughout the …

Disease resistance in coral is mediated by distinct adaptive and plastic gene expression profiles

NJ MacKnight, BA Dimos, KM Beavers, EM Muller… - Science …, 2022 - science.org
Infectious diseases are an increasing threat to coral reefs, resulting in altered community
structure and hindering the functional contributions of disease-susceptible species. We …

[HTML][HTML] Microbial dysbiosis reflects disease resistance in diverse coral species

NJ MacKnight, K Cobleigh, D Lasseigne… - Communications …, 2021 - nature.com
Disease outbreaks have caused significant declines of keystone coral species. While
forecasting disease outbreaks based on environmental factors has progressed, we still lack a …

[HTML][HTML] Advances in coral immunity 'omics in response to disease outbreaks

…, JR Guyon, A Hawthorn, NJ MacKnight… - Frontiers in Marine …, 2022 - frontiersin.org
Coral disease has progressively become one of the most pressing issues affecting coral reef
survival. In the last 50 years, several reefs throughout the Caribbean have been severely …

[HTML][HTML] Annotated genome and transcriptome of the endangered Caribbean mountainous star coral (Orbicella faveolata) using PacBio long-read sequencing

…, N Andrade Rodriguez, LM Isma, NJ MacKnight… - BMC genomics, 2024 - Springer
Long-read sequencing is revolutionizing de-novo genome assemblies, with continued
advancements making it more readily available for previously understudied, non-model organisms…

Adaptive variation in homologue number within transcript families promotes expression divergence in reef‐building coral

B Dimos, M Emery, K Beavers, N MacKnight… - Molecular …, 2022 - Wiley Online Library
Gene expression, especially in multispecies experiments, is used to gain insight into the
genetic basis of how organisms adapt and respond to changing environments. However, …

Responding to threats both foreign and domestic: NOD-like receptors in corals

…, CC Butler, CA Ricci, NJ MacKnight… - Integrative and …, 2019 - academic.oup.com
Historically mechanisms with which basal animals such as reef-building corals use to respond
to changing and increasingly stressful environments have remained elusive. However, …

[HTML][HTML] An Acute Permethrin Exposure Causes Significant Microbial Shifts in Montastraea cavernosa

NJ MacKnight, L Arick, AC Crawford… - Frontiers in Marine …, 2022 - frontiersin.org
Insecticide use is common in developed tropical regions where it may enter coastal reef
ecosystems through land-based sources. This local introduction of contaminants could affect …

Gene Family Complexity and Expression Divergence as a Mechanism of Adaptation In Coral

B Dimos, M Emery, N MacKnight, M Brandt, J Demuth… - bioRxiv, 2021 - biorxiv.org
Gene family complexity and its influence on expression dynamics has long been theorized
to be an important source of adaptation in natural systems through providing novel genetic …