Local secretion of cytokines by T cells within the bronchial mucosa, with consequent
selective eosinophil influx, has been implicated in the pathogenesis of bronchial asthma. The …

Background and Aim Functional dyspepsia ( FD ), defined by unexplained pain or discomfort
centered in the upper abdomen, is common. Diagnosis and treatment of FD based on the …

Objective Antitumour necrosis factor (anti-TNF) drugs impair protective immunity following
pneumococcal, influenza and viral hepatitis vaccination and increase the risk of serious …

Eosinophils are potent innate immune cells that home to the gastrointestinal tract where they
participate in host immunity to luminal pathogens, and help to maintain intestinal epithelial …

Crohn’s disease (CD) is a chronic inflammatory disease of the gastrointestinal tract (GIT).
Cigarette smoke (CS) exposure and chronic obstructive pulmonary disease (COPD) are risk …

Regulatory T cells (Tregs) play a pivotal role in maintaining immunological tolerance, but
they can also play a detrimental role by preventing antitumor responses. Here, we …

Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) in Western countries is
characterized by eosinophilia, IgE production, and T H 2 cytokine expression. Type 2 innate …

Objective Antitumour necrosis factor (TNF) drugs impair serological responses following
SARS-CoV-2 vaccination. We sought to assess if a third dose of a messenger RNA (mRNA)-…

The induction of human CD4 + Th1 cells requires autocrine stimulation of the complement
receptor CD46 in direct crosstalk with a CD4 + T cell-intrinsic NLRP3 inflammasome. However…

Citizen science can increase the scope of research in the marine environment; however, it
suffers from necessitating specialized training and simplified methodologies that reduce …