Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction
Medically important flaviviruses cause diverse disease pathologies and collectively are
responsible for a major global disease burden. A contributing factor to pathogenesis is secreted …
responsible for a major global disease burden. A contributing factor to pathogenesis is secreted …
[HTML][HTML] SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling
…, B Castillo-Rojas, V Servellita, NTN Lo… - Nature …, 2022 - nature.com
Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction within the
lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory …
lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory …
[HTML][HTML] Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation
…, M Patana, TA Gomberg, C Malvar, NTN Lo… - PLoS …, 2019 - journals.plos.org
Arthropod-borne flaviviruses cause life-threatening diseases associated with endothelial
hyperpermeability and vascular leak. We recently found that vascular leak can be triggered by …
hyperpermeability and vascular leak. We recently found that vascular leak can be triggered by …
[HTML][HTML] A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes
… in the pat1 gene (pat1::Tn) that was previously isolated in a … the pat1::Tn mutation by generating
a strain (pat1::Tn pat1 + ) … ::Tn mutant, and a restoration of the band in the pat1::Tn pat1 + …
a strain (pat1::Tn pat1 + ) … ::Tn mutant, and a restoration of the band in the pat1::Tn pat1 + …
Molecular determinants of tissue specificity of flavivirus nonstructural protein 1 interaction with endothelial cells
Members of the mosquito-borne flavivirus genus such as dengue (DENV), West Nile (WNV),
and Zika (ZIKV) viruses cause distinct diseases and affect different tissues. We previously …
and Zika (ZIKV) viruses cause distinct diseases and affect different tissues. We previously …
Characterization of a protective antibody against dengue virus non-structural protein 1 (NS1) reveals critical domains required for NS1-triggered pathogenesis
Dengue virus (DENV) is a medically important, mosquito-borne flavivirus that infects up to
390 million people annually. A signature of severe DENV infection is vascular leak, which can …
390 million people annually. A signature of severe DENV infection is vascular leak, which can …
SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling (preprint)
…, DR Glasner, B Castillo-Rojas, V Servellita, NTN Lo… - 2021 - pesquisa.bvsalud.org
Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction within the
lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory …
lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory …
[HTML][HTML] Conversational agents in health care: scoping review of their behavior change techniques and underpinning theory
L Martinengo, AI Jabir, WWT Goh, NYW Lo… - Journal of Medical …, 2022 - jmir.org
Background Conversational agents (CAs) are increasingly used in health care to deliver
behavior change interventions. Their evaluation often includes categorizing the behavior …
behavior change interventions. Their evaluation often includes categorizing the behavior …
Competition between LO and TO phonon scattering in GaAs/GaAlAs heterojunctions
MA Brummell, DR Leadley, RJ Nicholas, JJ Harris… - Surface Science, 1988 - Elsevier
… The resonance positions give phonon frequencies closer to the bulk TO phonon than the
bulk LO value when the field is perpendicular to the heterojunction interface, but move up …
bulk LO value when the field is perpendicular to the heterojunction interface, but move up …
Molecular determinants of flavivirus non-structural protein 1
NT Lo - 2022 - escholarship.org
Molecular determinants of flavivirus non-structural protein 1 by Nicholas Lo Tzu Ning A
dissertation submitted in partial fulf … Nicholas Lo Tzu Ning … Nicholas Lo Tzu Ning …
dissertation submitted in partial fulf … Nicholas Lo Tzu Ning … Nicholas Lo Tzu Ning …