Although Drosophila systemic immunity is extensively studied, little is known about the fly's
intestine-specific responses to bacterial infection. Global gene expression analysis of …

Gut homeostasis is controlled by both immune and developmental mechanisms, and its
disruption can lead to inflammatory disorders or cancerous lesions of the intestine. While the …

Bacillus thuringiensis is the most widely applied biological insecticide and is used to manage
insects that affect forestry and agriculture and transmit human and animal pathogens. This …

Little is known about bacteria associated with Lepidoptera, the large group of mostly
phytophagous insects comprising the moths and butterflies. We inventoried the larval midgut …

The increasing prevalence of antibiotic-resistant bacteria is a global threat to public health.
Agricultural use of antibiotics is believed to contribute to the spread of antibiotic resistance, …

There is growing interest in using Drosophila melanogaster to elucidate mechanisms that
underlie the complex relationships between a host and its microbiota. In addition to the many …

Intestinal homeostasis is achieved, in part, by the integration of a complex set of mechanisms
that eliminate pathogens and tolerate the indigenous microbiota. Drosophila melanogaster …

To elucidate mechanisms underlying the complex relationships between a host and its
microbiota, we used the genetically tractable model Drosophila melanogaster . Consistent with …

Background Gut homeostasis is central to whole organism health, and its disruption is
associated with a broad range of pathologies. Following damage, complex physiological events …

Background Gut microbiota contribute to the health of their hosts, and alterations in the
composition of this microbiota can lead to disease. Previously, we demonstrated that indigenous …