Candida albicans is the primary fungal pathogen of humans. Despite the need for novel drugs
to combat fungal infections [Sobel, JD (2000) Clin Infectious Dis 30: 652], antifungal drug …

INTRODUCTION In all eukaryotic cells, lipid droplets (LDs) store and supply essential lipids
to produce signaling molecules, membrane building blocks, and metabolic energy. The LD …

Candida albicans is a prevalent fungal pathogen amongst the immunocompromised
population, causing both superficial and life-threatening infections. Since C. albicans is diploid, …

Dysfunction of caveolae is involved in human muscle disease, although the underlying
molecular mechanisms remain unclear. In this paper, we have functionally characterized mouse …

Reliable and quantifiable high-resolution protein localization is critical for understanding
protein function. However, the time required to clone and characterize any protein of interest is …

Caveolae have been linked to many biological functions, but their precise roles are unclear.
Using quantitative whole-cell proteomics of genome-edited cells, we show that the oxidative …

Nuclear hormone receptors (NR) have been implicated as regulators of lipid and carbohydrate
metabolism. The orphan NR4A subgroup has emerged as regulators of metabolic function…

The embryonic notochord is a flexible structure present during development that serves as
scaffold for formation of the vertebrate spine. This rod-like organ is thought to have evolved in …

Caveolin‐1 (CAV1) is a structural protein of caveolae involved in lipid homeostasis and
endocytosis. Using newly generated pure Balb/C CAV1 null ( Balb/C CAV1−/−) mice, CAV1−/− …

Actin has an ill‐defined role in the trafficking of GLUT4 glucose transporter vesicles to the
plasma membrane ( PM ). We have identified novel actin filaments defined by the tropomyosin …