We report a chemically defined, efficient, scalable and reproducible protocol for differentiation
of human embryonic stem cells (hESCs) toward chondrocytes. HESCs are directed …

Stem cell-derived somatic cells represent an unlimited resource for basic and translational
science. Although promising, there are significant hurdles that must be overcome. Our focus is …

Background Human embryonic stem cells (hESCs) hold tremendous promise for cell
replacement therapies for a range of degenerative diseases. In order to provide cost-effective …

Permethrin is a pyrethroid insecticide used in dermally applied spot-on flea treatments for
dogs. Permethrin-based spot-on preparations are contraindicated in cats because of the high …

The role of individual supplements necessary for the self-renewal of human embryonic stem
(hES) cells is poorly characterized, and furthermore we have found that previously reported …

CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy) is the most common form of genetic stroke and vascular dementia syndrome …

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor β (TGFβ)
superfamily and have crucial roles during development; including mesodermal patterning …

Optogenetics is a rapidly advancing technology combining photochemical, optical, and
synthetic biology to control cellular behavior. Together, sensitive light-responsive optogenetic …

Mammalian placentation is dependent upon the action of trophoblast cells at the time of
implantation. Appropriate fetal growth, regulated by maternal nutrition and nutrient transport …

Cyanobacterial blooms are often associated with the presence of harmful natural compounds
which can cause adverse health effects in both humans and animals. One family of these …