User profiles for Nicola Bombieri

Nicola Bombieri

University of Verona
Verified email at univr.it
Cited by 1800

Human genetic diversity alters off-target outcomes of therapeutic gene editing

…, LY Lin, M Tognon, MA Nguyen, J Lin, N Bombieri… - Nature …, 2023 - nature.com
CRISPR gene editing holds great promise to modify DNA sequences in somatic cells to
treat disease. However, standard computational and biochemical methods to predict off-target …

Hornet: An efficient data structure for dynamic sparse graphs and matrices on gpus

F Busato, O Green, N Bombieri… - 2018 IEEE High …, 2018 - ieeexplore.ieee.org
Sparse data computations are ubiquitous in science and engineering. Unlike their dense
data counterparts, sparse data computations have less locality and more irregularity in their …

An efficient implementation of the Bellman-Ford algorithm for Kepler GPU architectures

F Busato, N Bombieri - IEEE Transactions on Parallel and …, 2015 - ieeexplore.ieee.org
Finding the shortest paths from a single source to all other vertices is a common problem in
graph analysis. The Bellman-Ford's algorithm is the solution that solves such a single-source …

CRISPRitz: rapid, high-throughput and variant-aware in silico off-target site identification for CRISPR genome editing

S Cancellieri, MC Canver, N Bombieri, R Giugno… - …, 2020 - academic.oup.com
Motivation Clustered regularly interspaced short palindromic repeats (CRISPR) technologies
allow for facile genomic modification in a site-specific manner. A key step in this process is …

[HTML][HTML] Grapes: A software for parallel searching on biological graphs targeting multi-core architectures

R Giugno, V Bonnici, N Bombieri, A Pulvirenti, A Ferro… - PloS one, 2013 - journals.plos.org
Biological applications, from genomics to ecology, deal with graphs that represents the
structure of interactions. Analyzing such data requires searching for subgraphs in collections of …

[PDF][PDF] HIFSuite: Tools for HDL code conversion and manipulation

N Bombieri, G Di Guglielmo, M Ferrari, F Fummi… - EURASIP Journal on …, 2010 - Springer
HIFSuite ia a set of tools and application programming interfaces (APIs) that provide support
for modeling and verification of HW/SW systems. The core of HIFSuite is the HDL …

BFS-4K: an efficient implementation of BFS for kepler GPU architectures

F Busato, N Bombieri - IEEE Transactions on Parallel and …, 2014 - ieeexplore.ieee.org
Breadth-first search (BFS) is one of the most common graph traversal algorithms and the
building block for a wide range of graph applications. With the advent of graphics processing …

A mutation model for the SystemC TLM 2.0 communication interfaces

N Bombieri, F Fummi, G Pravadelli - … on Design, automation and test in …, 2008 - dl.acm.org
Mutation analysis is a widely-adopted strategy in software testing with two main purposes:
measuring the quality of test suites, and identifying redundant code in programs. Similar …

Enabling gait analysis in the telemedicine practice through portable and accurate 3D human pose estimation

…, N Smania, M Bertucco, A Picelli, N Bombieri - Computer Methods and …, 2022 - Elsevier
Human pose estimation (HPE) through deep learning-based software applications is a
trend topic for markerless motion analysis. Thanks to the accuracy of the state-of-the-art …

Automatic abstraction of RTL IPs into equivalent TLM descriptions

N Bombieri, F Fummi… - IEEE Transactions on …, 2010 - ieeexplore.ieee.org
Transaction-level modeling (TLM) is the most promising technique to deal with the
increasing complexity of modern embedded systems. However, modeling a complex system …