Reduced lung function predicts mortality and is key to the diagnosis of chronic obstructive
pulmonary disease (COPD). In a genome-wide association study in 400,102 individuals of …

Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality
worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed …

Background Airway bacterial dysbiosis is a feature of chronic obstructive pulmonary disease
(COPD). However, there is limited comparative data of the lung microbiome between …

Capsule Although the White Stork avoids adverse weather conditions by modifying its arrival
and breeding, it cannot avoid extreme weather events during the breeding season. Aims To …

Background Antibiotic resistance is a major global threat. We hypothesised that the chronic
obstructive pulmonary disease (COPD) airway is a reservoir of antimicrobial resistance …

Rationale Eosinophils are associated with airway inflammation in respiratory disease.
Eosinophil production and survival is controlled partly by interleukin-5: anti-interleukin-5 agents …

EXCEED aims to develop understanding of the genetic, environmental and lifestyle-related
causes of health and disease. Cohorts like EXCEED, with broad consent to study multiple …

Objectives To assess whether residential proximity to industrial incinerators in England is
associated with increased risk of cancer incidence and mortality. Design Retrospective study …

Reduced lung function predicts mortality and is key to the diagnosis of COPD. In a genome-wide
association study in 400,102 individuals of European ancestry, we define 279 lung …

3. In the Fig. 3b table, the SPIROMICS row:“1.54, 1.38, 1.72, 4.47× 10–14, 988, 537”, should
be “1.55, 1.39, 1.74, 6.80× 10–14, 973, 526”; and the Meta-analysis row:“1.55, 1.48, 1.62, …