[HTML][HTML] Viral manipulation of STAT3: Evade, exploit, and injure
AA Roca Suarez, N Van Renne, TF Baumert… - PLoS …, 2018 - journals.plos.org
Signal transducer and activator of transcription 3 (STAT3) is a key regulator of numerous
physiological functions, including the immune response. As pathogens elicit an acute phase …
physiological functions, including the immune response. As pathogens elicit an acute phase …
Combined analysis of metabolomes, proteomes, and transcriptomes of hepatitis C virus–infected cells and liver to identify pathways associated with disease …
…, T Croonenborghs, AAR Suarez, N Van Renne… - Gastroenterology, 2019 - Elsevier
Background & Aims The mechanisms of hepatitis C virus (HCV) infection, liver disease
progression, and hepatocarcinogenesis are only partially understood. We performed genomic, …
progression, and hepatocarcinogenesis are only partially understood. We performed genomic, …
miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis
N Van Renne, AAR Suarez, FHT Duong, C Gondeau… - Gut, 2018 - gut.bmj.com
Background and aims HCV infection is a leading risk factor of hepatocellular carcinoma (HCC).
However, even after viral clearance, HCC risk remains elevated. HCV perturbs host cell …
However, even after viral clearance, HCC risk remains elevated. HCV perturbs host cell …
[HTML][HTML] Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation
…, F Giannone, RT Chung, N Slovic, N Van Renne… - JCI insight, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a leading cause of death among cirrhotic patients, for
which chemopreventive strategies are lacking. Recently, we developed a simple human cell-…
which chemopreventive strategies are lacking. Recently, we developed a simple human cell-…
[HTML][HTML] Strain-dependent porcine circovirus type 2 (PCV2) entry and replication in T-lymphoblasts
R Wei, N Van Renne, HJ Nauwynck - Viruses, 2019 - mdpi.com
Porcine circovirus type 2 (PCV2) is the etiological agent of PCV2-associated diseases (PCVAD).
PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte …
PCV2 targets lymphoblasts, and pigs suffering from PCVAD display lymphocyte …
[HTML][HTML] Anti-porcine circovirus type 2 (PCV2) antibody placental barrier leakage from sow to fetus: impact on the diagnosis of intra-uterine PCV2 infection
D Saha, RDP Sacristán, N Van Renne, L Huang… - Virologica …, 2014 - virosin.org
… Citation: Dipongkor Saha, Rubén Del Pozo Sacristán, Nicolaas Van Renne, Liping
Huang, Ruben Decaluwe, Annelies Michiels, Alfonso Lopez Rodriguez, Maria José …
Huang, Ruben Decaluwe, Annelies Michiels, Alfonso Lopez Rodriguez, Maria José …
A sequence of basic residues in the porcine circovirus type 2 capsid protein is crucial for its co-expression and co-localization with the replication protein
L Huang, N Van Renne, C Liu… - Journal of General …, 2015 - microbiologyresearch.org
Porcine circovirus type 2 (PCV2) encodes two major proteins: the replication protein (Rep)
and the capsid protein (Cap). Cap displays a conserved stretch of basic residues situated on …
and the capsid protein (Cap). Cap displays a conserved stretch of basic residues situated on …
[HTML][HTML] Dissecting clinical outcome of porcine circovirus type 2 with in vivo derived transcriptomic signatures of host tissue responses
N Van Renne, R Wei, N Pochet, HJ Nauwynck - BMC genomics, 2018 - Springer
Background Porcine Circovirus Type 2 (PCV2) is a pathogen that has the ability to cause
often devastating disease manifestations in pig populations with major economic implications. …
often devastating disease manifestations in pig populations with major economic implications. …
miR-135a-5p-mediated downregulation of protein-tyrosine phosphatase delta is a candidate driver of HCV-associated hepatocarcinogenesis
N Van Renne, AAR Suarez, FHT Duong, C Gondeau… - 2016 - gut.bmj.com
SUPPLEMENTARY INFORMATION miR-135a-5p-mediated downregulation of protein-tyrosine
phosphatase delta is a candidate driver of HCV Page 1 1 SUPPLEMENTARY …
phosphatase delta is a candidate driver of HCV Page 1 1 SUPPLEMENTARY …
Signaling of hepatitis C virus
J Lupberger, N Van Renne… - Signaling Pathways in …, 2015 - Wiley Online Library
This chapter describes how hepatitis C virus (HCV) interacts with host kinases and modulates
the activities of signaling pathways. HCV makes use of signal transduction in order to …
the activities of signaling pathways. HCV makes use of signal transduction in order to …