User profiles for Nicolas Alcaraz
 | Nicolas AlcarazUniversity of Copenhagen Verified email at cpr.ku.dk Cited by 765 |
[HTML][HTML] The evolutionary landscape of SARS-CoV-2 variant B. 1.1. 519 and its clinical impact in Mexico City
The SARS-CoV-2 pandemic is one of the most concerning health problems around the globe.
We reported the emergence of SARS-CoV-2 variant B.1.1.519 in Mexico City. We reported …
We reported the emergence of SARS-CoV-2 variant B.1.1.519 in Mexico City. We reported …
[PDF][PDF] Recycling of modified H2A-H2B provides short-term memory of chromatin states
Chromatin landscapes are disrupted during DNA replication and must be restored faithfully
to maintain genome regulation and cell identity. The histone H3-H4 modification landscape …
to maintain genome regulation and cell identity. The histone H3-H4 modification landscape …
[HTML][HTML] Symmetric inheritance of parental histones governs epigenome maintenance and embryonic stem cell identity
Modified parental histones are segregated symmetrically to daughter DNA strands during
replication and can be inherited through mitosis. How this may sustain the epigenome and cell …
replication and can be inherited through mitosis. How this may sustain the epigenome and cell …
The AIMe registry for artificial intelligence in biomedical research
We present the AIMe registry, a community-driven reporting platform for AI in biomedicine. It
aims to enhance the accessibility, reproducibility and usability of biomedical AI models, and …
aims to enhance the accessibility, reproducibility and usability of biomedical AI models, and …
[HTML][HTML] Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection
…, A Del Moral-Morales, N Alcaraz… - NPJ systems biology …, 2021 - nature.com
COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome
coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the …
coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the …
[HTML][HTML] Emergence and spread of the potential variant of interest (VOI) B. 1.1. 519 of SARS-CoV-2 predominantly present in Mexico
SARS-CoV-2 variants emerged in late 2020, and at least three variants of concern (B.1.1.7,
B.1.351, and P1) have been reported by WHO. These variants have several substitutions in …
B.1.351, and P1) have been reported by WHO. These variants have several substitutions in …
[HTML][HTML] KeyPathwayMiner 4.0: condition-specific pathway analysis by combining multiple omics studies and networks with Cytoscape
Background Over the last decade network enrichment analysis has become popular in
computational systems biology to elucidate aberrant network modules. Traditionally, these …
computational systems biology to elucidate aberrant network modules. Traditionally, these …
De novo pathway-based biomarker identification
Gene expression profiles have been extensively discussed as an aid to guide the therapy
by predicting disease outcome for the patients suffering from complex diseases, such as …
by predicting disease outcome for the patients suffering from complex diseases, such as …
KeyPathwayMinerWeb: online multi-omics network enrichment
We present KeyPathwayMinerWeb, the first online platform for de novo pathway enrichment
analysis directly in the browser. Given a biological interaction network (eg protein–protein …
analysis directly in the browser. Given a biological interaction network (eg protein–protein …
[HTML][HTML] Transcriptome analysis identifies GATA3-AS1 as a long noncoding RNA associated with resistance to neoadjuvant chemotherapy in locally advanced breast …
Breast cancer is one of the leading causes of mortality in women worldwide, neoadjuvant
chemotherapy has emerged as an option for the management of locally advanced breast …
chemotherapy has emerged as an option for the management of locally advanced breast …