Parkinson’s disease (PD) is histologically described by the deposition of α-synuclein, whose
accumulation in Lewy bodies causes dopaminergic neuronal death. Although most of PD …

A remarkable number of guanine-rich sequences with potential to adopt non-canonical
secondary structures called G-quadruplexes (or G4 DNA) are found within gene promoters. …

Neutrophils participate in the maintenance of host integrity by releasing various cytotoxic
proteins during degranulation. Due to recent advances, a major role has been attributed to …

MiRNAs are increasingly recognized as biomarkers for the diagnosis of cancers where they
are profiled from tumor tissue (intracellular miRNAs) or serum/plasma samples (extracellular …

Background: Over the past years, some members of the family of suppressor of cytokine
signalling (SOCS) proteins have emerged as potential tumour suppressors. This study aimed at …

The VRC01 Antibody Mediated Prevention (AMP) efficacy trials conducted between 2016 and
2020 showed for the first time that passively administered broadly neutralizing antibodies (…

Advances in single-cell RNA sequencing have allowed for the identification of cellular
subtypes on the basis of quantification of the number of transcripts in each cell. However, cells …

RNA subcellular localization has recently emerged as a widespread phenomenon, which
may apply to the majority of RNAs. The two main sources of data for characterization of RNA …

In the Antibody Mediated Prevention (AMP) trials (HVTN 704/HPTN 085 and HVTN 703/HPTN
081), prevention efficacy (PE) of the monoclonal broadly neutralizing antibody (bnAb) …

Background Rice molecular genetics, breeding, genetic diversity, and allied research (such
as rice-pathogen interaction) have adopted sequencing technologies and high-density …