User profiles for Nicolas Perrot

Nicolas Perrot

McMaster University
Verified email at crlb-gmel.ca
Cited by 665

Characterization of complex adnexal masses: value of adding perfusion-and diffusion-weighted MR imaging to conventional MR imaging

I Thomassin-Naggara, I Toussaint, N Perrot, R Rouzier… - Radiology, 2011 - pubs.rsna.org
Purpose To retrospectively determine the value of adding perfusion-weighted (PW) and
diffusion-weighted (DW) sequences to a conventional magnetic resonance (MR) imaging …

Ovarian-adnexal reporting data system magnetic resonance imaging (O-RADS MRI) score for risk stratification of sonographically indeterminate adnexal masses

…, C Balleyguier, C Malhaire, NF Perrot… - JAMA network …, 2020 - jamanetwork.com
Importance Approximately one-quarter of adnexal masses detected at ultrasonography are
indeterminate for benignity or malignancy, posing a substantial clinical dilemma. Objective …

[PDF][PDF] Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

…, CA Emdin, E Gobeil, N Taba, ME Haas, N Perrot… - Cell Reports …, 2021 - cell.com
Non-alcoholic fatty liver disease (NAFLD) is a complex disease linked to several chronic
diseases. We aimed at identifying genetic variants associated with NAFLD and evaluating their …

Elevated lipoprotein (a) and risk of atrial fibrillation: an observational and Mendelian randomization study

…, M Chong, S Narula, N Perrot… - Journal of the American …, 2022 - jacc.org
Background Atrial fibrillation (AF) is a cardiac arrhythmia associated with an elevated risk of
stroke, heart failure, and mortality. However, preventative therapies are needed with …

Long-term results of hysteroscopic myomectomy in 235 patients

V Polena, JL Mergui, N Perrot, C Poncelet… - European Journal of …, 2007 - Elsevier
OBJECTIVE: To assess the efficacy of transcervical resection of submucous fibroids according
to type and size. MATERIALS AND METHODS: Retrospective follow-up of 235 women …

GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia

M Chong, P Mohammadi-Shemirani, N Perrot… - Elife, 2022 - elifesciences.org
… Author contributions Michael Chong, Conceptualization, Data curation, Formal analysis,
Methodology, Validation, Visualization, Writing – original draft, Writing – review and editing; …

[HTML][HTML] Ideal cardiovascular health influences cardiovascular disease risk associated with high lipoprotein (a) levels and genotype: the EPIC-Norfolk prospective …

N Perrot, R Verbeek, M Sandhu, SM Boekholdt… - Atherosclerosis, 2017 - Elsevier
Background and aims Lipoprotein(a) (Lp[a]) is a strong genetic risk factor for cardiovascular
disease (CVD). The American Heart Association has prioritised seven cardiovascular health …

Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis

N Perrot, V Valerio, D Moschetta, SM Boekholdt… - Basic to Translational …, 2020 - jacc.org
The authors investigated whether PCSK9 inhibition could represent a therapeutic strategy
in calcific aortic valve stenosis (CAVS). A meta-analysis of 10 studies was performed to …

[HTML][HTML] A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets

…, S Mao, M Chong, C Judge, N Pathan, N Perrot… - Nature …, 2023 - nature.com
Identification of gene-by-environment interactions (GxE) is crucial to understand the interplay
of environmental effects on complex traits. However, current methods evaluating GxE on …

Refining the regulatory region upstream of SOX9 associated with 46,XX testicular disorders of Sex Development (DSD)

…, R Harbuz, R Bhouri, N Perrot… - American journal of …, 2015 - Wiley Online Library
Disorders of Sex Development (DSD) are a heterogeneous group of disorders affecting gonad
and/or genito‐urinary tract development and usually the endocrine‐reproductive system. …