The Listeria monocytogenes genome includes a large family of proteins harbouring leucine-rich
repeats known as internalins (Inl). The generation of novel mutants and comparative …

Antibiotic therapy often fails to eliminate a fraction of transiently refractory bacteria, causing
relapses and chronic infections. Multiple mechanisms can induce such persisters with high …

Intracellular bacterial pathogens subvert the endocytic bactericidal pathway to form specific
replication-permissive compartments termed pathogen vacuoles or inclusions. To this end, …

The food-borne pathogen Listeria monocytogenes is adapted to a diversity of environments,
such as soil, food, body fluids, and the cytosol of eukaryotic cells. The transition between …

The water-borne bacterium Legionella pneumophila is the causative agent of Legionnaires’
disease. In the environment, the opportunistic pathogen colonizes different niches, including …

The pathogenic bacterium Legionella pneumophila replicates in host cells within a distinct
ER ‐associated compartment termed the Legionella‐containing vacuole ( LCV ). How the …

By engulfing potentially harmful microbes, professional phagocytes are continually at risk
from intracellular pathogens. To avoid becoming infected, the host must kill pathogens in the …

The facultative intracellular bacterium Legionella pneumophila replicates in environmental
amoebae and in lung macrophages, and causes Legionnaires’ disease. Here we show that L…

The Gram‐negative bacterium Legionella pneumophila is the causative agent of Legionnaires'
disease and replicates in amoebae and macrophages within a distinct compartment, the …

Ral proteins are small GTP ases that play critical roles in normal physiology and in
oncogenesis. There is little information on the GTP ase‐activating proteins ( GAP s) that …