As with many other viruses, the initial cell attachment of rotaviruses, which are the major
causative agent of infantile gastroenteritis, is mediated by interactions with specific cellular …

Urinary tract infections (UTIs) are responsible for an estimated 7 million office visits, 1 million
emergency room visits, and 100,000 hospitalizations each year, accounting for some 25% …

Antibiotic treatment of osteomyelitis has evolved substantially over the past 80 years.
Traditional teachings (eg, that antimicrobials must be given parenterally, selected based upon …

Noroviruses, in the genus Norovirus, are a significant cause of viral gastroenteritis in humans
and animals. For almost 50 years, the lack of a cultivation system for human noroviruses (…

Human noroviruses (HuNoVs) are the leading cause of epidemic and sporadic acute
gastroenteritis worldwide. We previously demonstrated human intestinal stem cell-derived …

Purpose Norovirus is the leading cause of acute epidemic gastroenteritis among children
under the age of 5 years and adults in the United States and in adults worldwide, accounting …

Naturally occurring bovine-human reassortant rotaviruses with a P[11] VP4 genotype exhibit
a tropism for neonates. Interaction of the VP8* domain of the spike protein VP4 with sialic …

Staphylococcus aureus bacteremia (SAB) causes considerable morbidity and mortality and
requires comprehensive assessment for metastatic infection. The roles of routine imaging …

Background An estimated 6500 undocumented immigrants with end-stage renal disease (ESRD)
live in the United States. Those living in states that do not provide undocumented …

Background Based primarily on in vitro and animal models, with little data directly addressing
patient outcomes, current guidelines recommend treating staphylococcal prosthetic valve …