C57BL/6J (B6) and DBA/2J (D2) are two of the most commonly used inbred mouse strains
in neuroscience research. However, the only currently available mouse genome is based …

Evidence for genetic linkage to alcohol and other substance dependence phenotypes in areas
of the human and mouse genome have now been reported with some consistency across …

It is well established that chronic heavy alcohol drinking (CHD) results in significant organ
damage, increased susceptibility to infections, and poor outcomes following injury. In contrast, …

Physiological dependence and associated withdrawal episodes can constitute a powerful
motivational force that perpetuates drug use and abuse. Using robust behavioral models of …

Methamphetamine (MA) and neurotransmitter precursors and metabolites such as tyramine,
octopamine, and β-phenethylamine stimulate the G protein-coupled trace amine-associated …

Here, we map a quantitative trait locus (QTL) with a large effect on predisposition to barbiturate
(pentobarbital) withdrawal to a 0.44 Mb interval of mouse chromosome 1 syntenic with …

Prenatal alcohol exposure (PAE), like other pregnancy complications, can result in placental
insufficiency and fetal growth restriction, although the linking causal mechanisms are …

Background The Monkey Alcohol Tissue Research Resource (MATRR) is a repository and
analytics platform for detailed data derived from well‐documented nonhuman primate (NHP) …

10.7554/eLife.46472.001 We identified a locus on mouse chromosome 10 that accounts for
60% of the genetic variance in methamphetamine intake in mice selectively bred for high …

With the recent completion of the Perlegen–US National Institute of Environmental Health
Sciences mouse resequencing project 1, which adds 8 million single nucleotide …