[HTML][HTML] Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma

…, E Teufel, S Han, L Haertle, N Banholzer… - Communications …, 2023 - nature.com
The treatment landscape in multiple myeloma (MM) is shifting from genotoxic drugs to
immunotherapies. Monoclonal antibodies, immunoconjugates, T-cell engaging antibodies and …

[HTML][HTML] Is mRNA decapping by ApaH like phosphatases present in eukaryotes beyond the Kinetoplastida?

PA Castañeda Londoño, N Banholzer… - BMC Ecology and …, 2021 - Springer
Background ApaH like phosphatases (ALPHs) originate from the bacterial ApaH protein and
have been identified in all eukaryotic super-groups. Only two of these proteins have been …

CARs are organized in nanodomains in the plasma membrane of T cells that accumulate at tumor contact sites

C Verbruggen, L Gehrke, N Banholzer, A Ghosh… - bioRxiv, 2023 - biorxiv.org
Chimeric antigen receptors (CARs) are synthetic immune receptors that are expressed in T
cells through genetic engineering. CAR-T cells have been successfully used to eradicate …

Impaired Death Receptor Signaling Mediates Cross-Resistance to Immunotherapy in MM

…, E Teufel, S Han, L Haertle, P Eiring, N Banholzer… - Blood, 2022 - ashpublications.org
The treatment landscape in various cancers is currently shifting from genotoxic drugs to
immunotherapy, such as monoclonal antibodies, immunoconjugates, T-cell engaging antibodies …

Is mRNA decapping activity of ApaH like phosphatases (ALPH's) the reason for the loss of cytoplasmic ALPH's in all eukaryotes but Kinetoplastida?

PAC Londono, N Banholzer, BP Bannerman, S Kramer - 2021 - researchsquare.com
Background: ApaH like phosphatases (ALPHs) originate from the bacterial ApaH protein and
are present in eukaryotes of all eukaryotic super-groups; still, only two proteins have been …

[HTML][HTML] The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and …

D Miranda-Saavedra, MJR Stark, JC Packer… - BMC genomics, 2007 - Springer
Background Microsporidia, parasitic fungi-related eukaryotes infecting many cell types in a
wide range of animals (including humans), represent a serious health threat in …

Ultrabright and efficient single-photon generation based on nitrogen-vacancy centres in nanodiamonds on a solid immersion lens

T Schröder, F Gädeke, MJ Banholzer… - New Journal of …, 2011 - iopscience.iop.org
Single photons are fundamental elements for quantum information technologies such as
quantum cryptography, quantum information storage and optical quantum computing. Colour …

Rapamycin destabilizes interleukin-3 mRNA in autocrine tumor cells by a mechanism requiring an intact 3′ untranslated region

R Banholzer, APK Nair, HH Hirsch… - … and cellular biology, 1997 - Am Soc Microbiol
We analyzed the effect of rapamycin on autocrine mast cell tumor lines with abnormally stable
interleukin-3 (IL-3) transcripts due to a defect in mRNA degradation. Rapamycin inhibited …

[PDF][PDF] Sunday, April 24, 2016

H CONVOCATION - digitalcommons.lindenwood.edu
NICOLE HENSLEY This award is given to an outstanding senior female NCAA student-athlete
who has excelled in academics at Lindenwood University and who has been a team …

The impact of postbariatric hypoglycaemia on driving performance: a randomized, single‐blind, two‐period, crossover study in a driving simulator

…, D Herzig, J Meier, N Banholzer… - Diabetes, obesity …, 2021 - Wiley Online Library
Postbariatric hypoglycaemia (PBH) is an increasingly recognized complication of bariatric
surgery, but its effect on daily functioning remains unclear. In this randomized, single‐blind, …