Classification of electrophysiological and morphological neuron types in the mouse visual cortex

…, CA Anastassiou, E Barkan, K Bickley, N Blesie… - Nature …, 2019 - nature.com
Understanding the diversity of cell types in the brain has been an enduring challenge and
requires detailed characterization of individual neurons in multiple dimensions. To …

Classification of electrophysiological and morphological types in mouse visual cortex

…, D Feng, C Anastassiou, E Barkan, K Bickley, N Blesie… - BioRxiv, 2018 - biorxiv.org
Understanding the diversity of cell types in the brain has been an enduring challenge and
requires detailed characterization of individual neurons in multiple dimensions. To profile …

Targeting Sialyl-Thomsen nouveau (STn) antigen with the SGN-STNV antibody-drug conjugate is effective in preclinical studies

…, N Hansen, R Lawrence, S Anderson, N Blesie… - Cancer Research, 2021 - AACR
Targeting glyco-epitopes with antibody-drug conjugates (ADCs) provides a unique advantage
as multiple cell surface proteins expressing the same carbohydrate can be harnessed to …

Abstract C113: Discovery of a novel auristatin antibody drug conjugate drug linker with equal efficacy and reduced bone marrow toxicity compared to vedotin

…, R Yumul, EE McKinney, S Blackburn, N Blesie… - Molecular Cancer …, 2023 - AACR
There are four vedotin drug linker containing antibody drug conjugates currently approved
for treating cancer patients, proving that this technology platform is an effective modality for …

Novel auristatins with high activity on efflux-positive models and demonstrable bystander activity

…, M Zaval, M Quick, S Sandall, KK Emmerton, N Blesie… - Cancer Research, 2018 - AACR
Auristatins are a class of clinically validated antimitotic agents utilized as payloads in
antibody-drug conjugates (ADCs). Auristatins display many of the desirable properties necessary …

Inferring cortical function in the mouse visual system through large-scale systems neuroscience

M Hawrylycz, C Anastassiou… - Proceedings of the …, 2016 - National Acad Sciences
The scientific mission of the Project MindScope is to understand neocortex, the part of the
mammalian brain that gives rise to perception, memory, intelligence, and consciousness. We …

Large-scale unsupervised discovery of excitatory morphological cell types in mouse visual cortex

MA Weis, S Papadopoulos, L Hansel, T Lüddecke… - bioRxiv, 2022 - biorxiv.org
Neurons in the neocortex exhibit astonishing morphological diversity which is critical for
properly wiring neural circuits and giving neurons their functional properties. The extent to which …

[PDF][PDF] Dear friends

GBP Arts - 2010 - scholarworks.uni.edu
The combined choirs and Wind Symphony were met with roaring applause and accolades
following the performance. The Dalai Lama himself was so moved by the piece that, after …

[BOOK][B] Learning to predict in networks with heterogeneous and dynamic synapses

D Burnham - 2021 - search.proquest.com
A salient difference between artificial and biological neural networks is the complexity and
diversity of individual units in the latter (Tasic et al., 2018). This remarkable diversity is present …

Model descriptions in neuroscience: computational performance and collaboration

P Garcia-Rodriguez, AP Davison, L Sharma… - 2022 - hal.science
This report reviews the state-of-the-art of model descriptions for largescale neuronal network
models in computational neuroscience, with a particular focus on issues of collaborative …