Spindle orientation: a question of complex positioning

DT Bergstralh, NS Dawney, D St Johnston - Development, 2017 - journals.biologists.com
The direction in which a cell divides is determined by the orientation of its mitotic spindle at
metaphase. Spindle orientation is therefore important for a wide range of developmental …

Tissue tension and not interphase cell shape determines cell division orientation in the Drosophila follicular epithelium

…, AV Skeeters, TJ Nádasi, NS Dawney… - The EMBO …, 2019 - embopress.org
We investigated the cell behaviors that drive morphogenesis of the Drosophila follicular
epithelium during expansion and elongation of early‐stage egg chambers. We found that cell …

Pins is not required for spindle orientation in the Drosophila wing disc

…, I Kujawiak, NS Dawney, J Zhu, S Cooper… - …, 2016 - journals.biologists.com
In animal cells, mitotic spindles are oriented by the dynein/dynactin motor complex, which
exerts a pulling force on astral microtubules. Dynein/dynactin localization depends on Mud/…

[HTML][HTML] The mechanical influence of densification on epithelial architecture

C Cammarota, NS Dawney, PM Bellomio… - PLOS Computational …, 2024 - journals.plos.org
Epithelial tissues are the most abundant tissue type in animals, lining body cavities and
generating compartment barriers. The function of a monolayered epithelial tissue–whether …

A novel tool for the unbiased characterization of epithelial monolayer development in culture

NS Dawney, C Cammarota, Q Jia… - Molecular Biology of …, 2023 - Am Soc Cell Biol
The function of an epithelial tissue is intertwined with its architecture. Epithelial tissues are
often described as pseudo–two-dimensional, but this view may be partly attributed to …

[HTML][HTML] The Mechanical Influence of Densification on Initial Epithelial Architecture

C Cammarota, NS Dawney, PM Bellomio, M Jüng… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Epithelial tissues are the most abundant tissue type in animals, lining body cavities and
generating compartment barriers. The function of a monolayer epithelium–whether protective, …

Competition between cell-cell and cell-substrate adhesion determines epithelial monolayer architecture in culture

CM Cammarota, NS Dawney, Q Jia, MM Jüng… - bioRxiv, 2021 - biorxiv.org
Organ surfaces are lined by epithelial monolayers - sheets of cells that are one-cell thick.
This architecture underlies tissue function, and its loss is associated with disease, including …

Bimodal Spindle Orientation Drives Tissue Regularity in a Proliferating Epithelium

TM Finegan, D Na, AV Skeeters, NS Dawney… - bioRxiv, 2017 - biorxiv.org
We investigated the relationship between proliferation and tissue topology in an epithelial
tissue undergoing elongation. We found that cell division is not required for elongation of the …

A novel tool for the unbiased characterization of epithelial monolayer development in

SD Nicole, C Cammarota, Q Jia, A Shipley, A Joseph - Apoptosis - Am Soc Cell Biol
The function of an epithelial tissue is intertwined with its architecture. Epithelial tissues are
often described as pseudo-two-dimensional, but this view may be partly attributed to …

Characterizing the Development of Epithelial Monolayers in Culture

NS Dawney - 2023 - search.proquest.com
Epithelial tissues are the most common tissue type within our bodies. Epithelia have a wide
range of functions, including but not limited to, protection, absorption, and secretion. To …