Progressive functional decline in the epilepsies is largely unexplained. We formed the
ENIGMA-Epilepsy consortium to understand factors that influence brain measures in epilepsy, …

BACKGROUND: Mesial temporal lobe epilepsy (mTLE) with hippocampus sclerosis (HS) is
an important cause for focal epilepsy. In this study, we explored the integrity of connecting …

Objective: To determine nonmotor signs (NMS) and evaluate the utility of several diagnostic
tools in patients with de novo Parkinson disease (PD). Methods: This is a large single-center …

Anterior temporal lobe resection is often complicated by superior quadrantic visual field
deficits (VFDs). In some cases this can be severe enough to prohibit driving, even if a patient is …

Epilepsy is increasingly conceptualized as a network disorder. In this cross-sectional mega-analysis,
we integrated neuroimaging and connectome analysis to identify network …

Objectives The objectives of this study were to investigate (1) the annual rate of progression
of motor and cognitive symptoms and (2) baseline predictors of different modalities for this …

The epilepsies are commonly accompanied by widespread abnormalities in cerebral white
matter. ENIGMA-Epilepsy is a large quantitative brain imaging consortium, aggregating data …

Voxel‐based morphometry (VBM) shows a differentiated pattern in patients with atypical
Parkinson syndrome but so far has had little impact in individual cases. It is desirable to …

Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations, but
associations between neurobiological mechanisms and macroscale connectomics remain …

Objective: This was a longitudinal single-center cohort study to comprehensively explore
multimodal progression markers for Parkinson disease (PD) in patients with recently diagnosed …