[HTML][HTML] Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?
Y Vercoulen, NH van Teijlingen, IM de Kleer… - Arthritis research & …, 2009 - Springer
Juvenile idiopathic arthritis (JIA) is a disease characterized by chronic joint inflammation,
caused by a deregulated immune response. In patients with JIA, heat shock proteins (HSPs) …
caused by a deregulated immune response. In patients with JIA, heat shock proteins (HSPs) …
HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3
…, JK Sprokholt, NH van Teijlingen… - Nature …, 2017 - nature.com
The mechanisms by which human immunodeficiency virus 1 (HIV-1) avoids immune surveillance
by dendritic cells (DCs), and thereby prevents protective adaptive immune responses, …
by dendritic cells (DCs), and thereby prevents protective adaptive immune responses, …
[HTML][HTML] Selection of an HLA-C* 03: 04-restricted HIV-1 p24 gag sequence variant is associated with viral escape from KIR2DL3+ natural killer cells: data from an …
…, JM Carlson, NH van Teijlingen… - PLoS …, 2015 - journals.plos.org
Background Viruses can evade immune surveillance, but the underlying mechanisms are
insufficiently understood. Here, we sought to understand the mechanisms by which natural …
insufficiently understood. Here, we sought to understand the mechanisms by which natural …
[HTML][HTML] HLA-Cw* 0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function
L Fadda, C Körner, S Kumar, NH Van Teijlingen… - PLoS …, 2012 - journals.plos.org
Accumulating evidence suggests an important role for Natural Killer (NK) cells in the control
of HIV-1 infection. Recently, it was shown that NK cell-mediated immune pressure can result …
of HIV-1 infection. Recently, it was shown that NK cell-mediated immune pressure can result …
[HTML][HTML] Probiotic gut microbiota isolate interacts with dendritic cells via glycosylated heterotrimeric pili
HLP Tytgat, NH van Teijlingen, RMA Sullan… - PloS one, 2016 - journals.plos.org
Mapping of the microbial molecules underlying microbiota-host interactions is key to
understand how microbiota preserve mucosal homeostasis. A pivotal family of such bacterial …
understand how microbiota preserve mucosal homeostasis. A pivotal family of such bacterial …
Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses
…, M Rumpret, FF Fuchsberger, NH van Teijlingen… - MBio, 2019 - Am Soc Microbiol
Staphylococcus aureus is a major cause of skin and soft tissue infections and aggravator of
the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to S. …
the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to S. …
[HTML][HTML] Vaginal dysbiosis associated-bacteria Megasphaera elsdenii and Prevotella timonensis induce immune activation via dendritic cells
NH van Teijlingen, LC Helgers… - Journal of reproductive …, 2020 - Elsevier
Dysbiosis of the vaginal microbiome as a result of overgrowth of anaerobic bacteria leads to
bacterial vaginosis (BV) which is associated with increased inflammation in the genital …
bacterial vaginosis (BV) which is associated with increased inflammation in the genital …
[HTML][HTML] Autophagy-enhancing drugs limit mucosal HIV-1 acquisition and suppress viral replication ex vivo
APM Cloherty, NH van Teijlingen, TJTHD Eisden… - Scientific reports, 2021 - nature.com
Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication.
However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 …
However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 …
[HTML][HTML] Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission
R Sarrami-Forooshani, AW Mesman, NH van Teijlingen… - Retrovirology, 2014 - Springer
Background Sexual transmission is the main route of HIV-1 infection and the CCR5-using (R5)
HIV-1 is predominantly transmitted, even though CXCR4-using (X4) HIV-1 is often …
HIV-1 is predominantly transmitted, even though CXCR4-using (X4) HIV-1 is often …
Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C* 03: 04 and modulate primary natural killer cell function
NH Van Teijlingen, A Hölzemer, C Körner… - Aids, 2014 - journals.lww.com
Objective: The aim of this study was to assess the consequence of sequence variations in
HLA-C* 03: 04-presented HIV-1 p24 Gag epitopes on binding of the inhibitory natural killer (NK…
HLA-C* 03: 04-presented HIV-1 p24 Gag epitopes on binding of the inhibitory natural killer (NK…