User profiles for Nils Schallner
 | Nils SchallnerDepartment of Anesthesiology and Intensiv Care Medicine, University Medical Center … Verified email at uniklinik-freiburg.de Cited by 1137 |
[HTML][HTML] T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10
…, D Delev, J Kernbach, P Franco, N Schallner… - Nature …, 2022 - nature.com
Despite recent advances in cancer immunotherapy, certain tumor types, such as
Glioblastomas, are highly resistant due to their tumor microenvironment disabling the anti-tumor …
Glioblastomas, are highly resistant due to their tumor microenvironment disabling the anti-tumor …
[HTML][HTML] Microglia regulate blood clearance in subarachnoid hemorrhage by heme oxygenase-1
N Schallner, R Pandit, R LeBlanc… - The Journal of …, 2015 - Am Soc Clin Investig
Subarachnoid hemorrhage (SAH) carries a 50% mortality rate. The extravasated erythrocytes
that surround the brain contain heme, which, when released from damaged red blood cells…
that surround the brain contain heme, which, when released from damaged red blood cells…
[HTML][HTML] Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury
J Biermann, WA Lagrèze, N Schallner, CI Schwer… - Molecular …, 2011 - ncbi.nlm.nih.gov
Purpose Retinal ischemia/reperfusion (I/R) injury plays an important role in the pathophysiology
of various ocular diseases. Retinal ganglion cells (RGCs) are particularly vulnerable to …
of various ocular diseases. Retinal ganglion cells (RGCs) are particularly vulnerable to …
Carbon monoxide preserves circadian rhythm to reduce the severity of subarachnoid hemorrhage in mice
N Schallner, JL Lieberum, D Gallo, RH LeBlanc III… - Stroke, 2017 - Am Heart Assoc
Background and Purpose— Subarachnoid hemorrhage (SAH) is associated with a temporal
pattern of stroke incidence. We hypothesized that natural oscillations in gene expression …
pattern of stroke incidence. We hypothesized that natural oscillations in gene expression …
[HTML][HTML] Carbon monoxide abrogates ischemic insult to neuronal cells via the soluble guanylate cyclase-cGMP pathway
Purpose Carbon monoxide (CO) is an accepted cytoprotective molecule. The extent and
mechanisms of protection in neuronal systems have not been well studied. We hypothesized …
mechanisms of protection in neuronal systems have not been well studied. We hypothesized …
[HTML][HTML] Argon inhalation attenuates retinal apoptosis after ischemia/reperfusion injury in a time-and dose-dependent manner in rats
F Ulbrich, N Schallner, M Coburn, T Loop, WA Lagrèze… - PloS one, 2014 - journals.plos.org
Purpose Retinal ischemia and reperfusion injuries (IRI) permanently affect neuronal tissue
and function by apoptosis and inflammation due to the limited regenerative potential of …
and function by apoptosis and inflammation due to the limited regenerative potential of …
[HTML][HTML] Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury
…, S Scheid, S Spassov, N Schallner… - Neural Regeneration …, 2021 - journals.lww.com
We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like
receptors (TLR) 2 and 4. The downstream transcription factors signal transducer and …
receptors (TLR) 2 and 4. The downstream transcription factors signal transducer and …
Isoflurane but not sevoflurane or desflurane aggravates injury to neurons in vitro and in vivo via p75NTR-NF-ĸB activation
N Schallner, F Ulbrich, H Engelstaedter… - Anesthesia & …, 2014 - journals.lww.com
BACKGROUND: General anesthesia in patients with or at risk for neuronal injury remains
challenging due to the controversial influence of volatile anesthetics on neuronal damage. We …
challenging due to the controversial influence of volatile anesthetics on neuronal damage. We …
Carbon monoxide controls microglial erythrophagocytosis by regulating CD36 surface expression to reduce the severity of hemorrhagic injury
S Kaiser, L Selzner, J Weber, N Schallner - Glia, 2020 - Wiley Online Library
Microglial erythrophagocytosis is crucial in injury response to hemorrhagic stroke. We
hypothesized that regulation of microglial erythrophagocytosis via HO‐1/CO depends on a …
hypothesized that regulation of microglial erythrophagocytosis via HO‐1/CO depends on a …
[HTML][HTML] Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies
Purpose Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against
type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early …
type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early …