Here, we describe single-tube long fragment read (stLFR), a technology that enables
sequencing of data from long DNA molecules using economical second-generation sequencing …

Background Since the completion of the Human Genome Project in 2003, it is estimated that
more than 200,000 individual whole human genomes have been sequenced. A stunning …

Massively parallel sequencing (MPS) on DNA nanoarrays provides billions of reads at relatively
low cost and enables a multitude of genomic applications. Further improvement in read …

Purpose We describe a novel syndrome in seven female patients with extreme developmental
delay and neoteny. Methods All patients in this study were female, aged 4 to 23 years, …

Single tube long fragment read (stLFR) technology enables efficient WGS, haplotyping, and
contig scaffolding. It is based on adding the same barcode sequence to sub-fragments of the …

Background Systematic errors can be introduced from DNA amplification during massively
parallel sequencing (MPS) library preparation and sequencing array formation. Polymerase …

Obtaining accurate sequences from long DNA molecules is very important for genome
assembly and other applications. Here we describe single tube long fragment read (stLFR), a …

… El Niño and La Niña conditions within the Tropical Pacific Ocean with El Niño typically
bringing drier than average conditions to eastern Australia, while La Niña brings wetter than …

Tropomyosin (Tpm) is a two-chained α-helical coiled-coil protein that binds to filamentous
actin (F-actin), and regulates its interactions with myosin by occupying three average positions …

Multimodal machine learning (MML) is a tempting multidisciplinary research area where
heterogeneous data from multiple modalities and machine learning (ML) are combined to solve …