[PDF][PDF] Activation of cGAS/STING pathway upon paramyxovirus infection

…, A Charpenay, S Dupichaud, KP Dhondt, N Aurine… - Iscience, 2021 - cell.com
During inflammatory diseases, cancer, and infection, the cGAS/STING pathway is known to
recognize foreign or self-DNA in the cytosol and activate an innate immune response. Here, …

[HTML][HTML] Nipah virus W protein harnesses nuclear 14-3-3 to inhibit NF-κB-induced proinflammatory response

…, C Dumont, M Iampietro, R Pelissier, N Aurine… - Communications …, 2021 - nature.com
Nipah virus (NiV) is a highly pathogenic emerging bat-borne Henipavirus that has caused
numerous outbreaks with public health concerns. It is able to inhibit the host innate immune …

[HTML][HTML] High pathogenicity of nipah virus from Pteropus lylei Fruit Bats, Cambodia

M Gaudino, N Aurine, C Dumont, J Fouret… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
We conducted an in-depth characterization of the Nipah virus (NiV) isolate previously
obtained from a Pteropus lylei bat in Cambodia in 2003 (CSUR381). We performed full-genome …

[HTML][HTML] Reprogrammed Pteropus Bat Stem Cells as A Model to Study Host-Pathogen Interaction during Henipavirus Infection

N Aurine, C Baquerre, M Gaudino, C Jean, C Dumont… - Microorganisms, 2021 - mdpi.com
Bats are natural hosts for numerous zoonotic viruses, including henipaviruses, which are
highly pathogenic for humans, livestock, and other mammals but do not induce clinical disease …

Type I interferon receptor signaling drives selective permissiveness of astrocytes and microglia to measles virus during brain infection

…, B Charvet, S Dussurgey, O Allatif, N Aurine… - Journal of …, 2019 - Am Soc Microbiol
Fatal neurological syndromes can occur after measles virus (MeV) infection of the brain. The
mechanisms controlling MeV spread within the central nervous system (CNS) remain poorly …

[HTML][HTML] Potentiel des organoïdes cérébraux comme modèles d'étude des neuropathologies chez les animaux domestiques

P Bertrand, N AURINE, LA Théo… - INRAE Productions …, 2023 - productions-animales.org
∎ Le cerveau est un organe particulièrement complexe et son accès est quasi impossible
sans perturber sa structure et son organisation intégrée. Développer des modèles in vitro …

Control of Nipah virus infection in mice by the host adaptors mitochondrial antiviral signaling protein (MAVS) and myeloid differentiation primary response 88 (MyD88)

M Iampietro, N Aurine, KP Dhondt… - The Journal of …, 2020 - academic.oup.com
Interferon (IFN) type I plays a critical role in the protection of mice from lethal Nipah virus (NiV)
infection, but mechanisms responsible for IFN-I induction remain unknown. In the current …

[HTML][HTML] Sequencing the genome of Indian flying fox, natural reservoir of nipah virus, using hybrid assembly and conservative secondary scaffolding

J Fouret, FG Brunet, M Binet, N Aurine… - Frontiers in …, 2020 - frontiersin.org
Indian fruit bats, flying fox Pteropus medius was identified as an asymptomatic natural host
of recently emerged Nipah virus, which is known to induce a severe infectious disease in …

[HTML][HTML] Intranasal exposure to Rift Valley fever virus live-attenuated strains leads to high mortality rate in immunocompetent mice

…, M Chabert, MP Confort, L Conquet, C Pulido, N Aurine… - Viruses, 2022 - mdpi.com
Rift Valley fever virus (RVFV) is a pathogenic arthropod-borne virus that can cause serious
illness in both ruminants and humans. The virus can be transmitted by an arthropod bite or …

STLV-1 Commonly targets neurons in the brain of asymptomatic non-human primates

…, V Moulin, B Rimbaud, R Lacoste, N Aurine… - Mbio, 2023 - Am Soc Microbiol
The human T-cell leukemia virus (HTLV)-1 is responsible for an aggressive neurodegenerative
disease (HAM/TSP) and multiple neurological alterations. The capacity of HTLV-1 to …