User profiles for Noah Alexander
 | Noah AlexanderUCLA Verified email at g.ucla.edu Cited by 2088 |
[HTML][HTML] Extensive sequencing of seven human genomes to characterize benchmark reference materials
…, A Sidow, Z Weng, Y Liu, CE Mason, N Alexander… - Scientific data, 2016 - nature.com
The Genome in a Bottle Consortium, hosted by the National Institute of Standards and
Technology (NIST) is creating reference materials and data for human genome sequencing, as …
Technology (NIST) is creating reference materials and data for human genome sequencing, as …
A robust benchmark for detection of germline large deletions and insertions
…, V Huang, A Rouette, N Alexander… - Nature …, 2020 - nature.com
New technologies and analysis methods are enabling genomic structural variants (SVs) to
be detected with ever-increasing accuracy, resolution and comprehensiveness. To help …
be detected with ever-increasing accuracy, resolution and comprehensiveness. To help …
[HTML][HTML] Nanopore DNA sequencing and genome assembly on the International Space Station
We evaluated the performance of the MinION DNA sequencer in-flight on the International
Space Station (ISS), and benchmarked its performance off-Earth against the MinION, Illumina …
Space Station (ISS), and benchmarked its performance off-Earth against the MinION, Illumina …
[PDF][PDF] Geospatial resolution of human and bacterial diversity with city-scale metagenomics
…, S Dhanraj, T Nawrin, Y Saletore, N Alexander… - Cell systems, 2015 - cell.com
The panoply of microorganisms and other species present in our environment influence human
health and disease, especially in cities, but have not been profiled with metagenomics at …
health and disease, especially in cities, but have not been profiled with metagenomics at …
[HTML][HTML] Comprehensive benchmarking and ensemble approaches for metagenomic classifiers
Background One of the main challenges in metagenomics is the identification of microorganisms
in clinical and environmental samples. While an extensive and heterogeneous set of …
in clinical and environmental samples. While an extensive and heterogeneous set of …
[HTML][HTML] Single-molecule sequencing detection of N6-methyladenine in microbial reference materials
The DNA base modification N6-methyladenine (m 6 A) is involved in many pathways related
to the survival of bacteria and their interactions with hosts. Nanopore sequencing offers a …
to the survival of bacteria and their interactions with hosts. Nanopore sequencing offers a …
A robust benchmark for germline structural variant detection
New technologies and analysis methods are enabling genomic structural variants (SVs) to
be detected with ever-increasing accuracy, resolution, and comprehensiveness. Translating …
be detected with ever-increasing accuracy, resolution, and comprehensiveness. Translating …
[HTML][HTML] Nanopore sequencing in microgravity
Rapid DNA sequencing and analysis has been a long-sought goal in remote research and
point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological …
point-of-care medicine. In microgravity, DNA sequencing can facilitate novel astrobiological …
[HTML][HTML] Genomic methods and microbiological technologies for profiling novel and extreme environments for the extreme microbiome project (XMP)
…, TM Rock, K McGrath, N Alexander… - Journal of …, 2017 - ncbi.nlm.nih.gov
The Extreme Microbiome Project (XMP) is a project launched by the Association of Biomolecular
Resource Facilities Metagenomics Research Group (ABRF MGRG) that focuses on …
Resource Facilities Metagenomics Research Group (ABRF MGRG) that focuses on …
[HTML][HTML] Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum
Malaria parasites possess the remarkable ability to maintain chronic infections that fail to
elicit a protective immune response, characteristics that have stymied vaccine development …
elicit a protective immune response, characteristics that have stymied vaccine development …