[HTML][HTML] Bacterial communities in women with bacterial vaginosis: high resolution phylogenetic analyses reveal relationships of microbiota to clinical criteria

S Srinivasan, NG Hoffman, MT Morgan, FA Matsen… - PloS one, 2012 - journals.plos.org
Background Bacterial vaginosis (BV) is a common condition that is associated with numerous
adverse health outcomes and is characterized by poorly understood changes in the …

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

AB Sparks, JE Rider, NG Hoffman… - Proceedings of the …, 1996 - National Acad Sciences
Src homology 3 (SH3) domains are conserved protein modules 50-70 amino acids long
found in a variety of proteins with important roles in signal transduction. These domains have …

Performance comparison of Illumina and ion torrent next-generation sequencing platforms for 16S rRNA-based bacterial community profiling

…, TT Harkins, BT Cookson, NG Hoffman - Applied and …, 2014 - Am Soc Microbiol
High-throughput sequencing of the taxonomically informative 16S rRNA gene provides a
powerful approach for exploring microbial diversity. Here we compare the performances of two …

[HTML][HTML] Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains

M Yamabhai, NG Hoffman, NL Hardison… - Journal of Biological …, 1998 - ASBMB
We screened a Xenopus laevis oocyte cDNA expression library with a Src homology 3 (SH3)
class II peptide ligand and identified a 1270-amino acid-long protein containing two Eps15 …

Metabolic signatures of bacterial vaginosis

…, MT Morgan, TL Fiedler, D Djukovic, NG Hoffman… - MBio, 2015 - Am Soc Microbiol
Bacterial vaginosis (BV) is characterized by shifts in the vaginal microbiota from Lactobacillus
dominant to a microbiota with diverse anaerobic bacteria. Few studies have linked specific …

[HTML][HTML] Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections

…, J Shendure, CC Lee, TT Harkins, NG Hoffman - PloS one, 2013 - journals.plos.org
Classifying individual bacterial species comprising complex, polymicrobial patient specimens
remains a challenge for culture-based and molecular microbiology techniques in common …

Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop

NG Hoffman, F Seillier-Moiseiwitsch, JH Ahn… - Journal of …, 2002 - Am Soc Microbiol
Isolates of human immunodeficiency virus type 1 (HIV-1) are classified according to the
chemokine receptor (coreceptor) used in conjunction with CD4 to target and enter cells: viruses …

A novel, multifunctional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes

V Ribon, JA Printen, NG Hoffman, BK Kay… - Molecular and cellular …, 1998 - Taylor & Francis
The protein product of the c-Cbl proto-oncogene is prominently tyrosine phosphorylated in
response to insulin in 3T3-L1 adipocytes and not in 3T3-L1 fibroblasts. After insulin-…

Marked variability of BK virus load measurement using quantitative real-time PCR among commonly used assays

NG Hoffman, L Cook, EE Atienza… - Journal of clinical …, 2008 - Am Soc Microbiol
BK virus (BKV) is the infectious cause of polyomavirus-associated nephropathy. Screening
guidelines for renal-transplant recipients define levels of viremia and viruria that are …

Prevalence of coronavirus disease 2019 infection and outcomes among symptomatic healthcare workers in Seattle, Washington

…, SV Olin, A Bryan, NG Hoffman… - Clinical Infectious …, 2020 - academic.oup.com
Background Healthcare workers (HCWs) who serve on the front lines of the coronavirus
disease 2019 (COVID-19) pandemic have been at increased risk for infection due to severe …