Feedback regulation is pervasive in biology at both the organismal and cellular level. In this
article, we explore the properties of a particular biomolecular feedback mechanism called …

We consider a group of Bayesian agents who try to estimate a state of the world θ through
interaction on a social network. Each agent v initially receives a private measurement of θ: a …

Many sensory systems, from vision and hearing in animals to signal transduction in cells,
respond to fold changes in signal relative to background. Responding to fold change requires …

As we begin to design increasingly complex synthetic biomolecular systems, it is essential to
develop rational design methodologies that yield predictable circuit performance. Here we …

A common feature of both biological and man-made systems is the use of feedback to
control their behavior. In this paper, we explore a particular model of biomolecular feedback …

Motifs, circuits, and networks are core conceptual elements in modern systems and synthetic
biology. While there are still undoubtedly more fascinating computations to discover at …

An approach combining genetic, proteomic, computational, and physiological analysis was
used to define a protein network that regulates fat storage in budding yeast (Saccharomyces …

Biomolecular feedback systems are now a central application area of interest within control
theory. While classical control techniques provide valuable insight into the function and …

Integral control is commonly used in mechanical and electrical systems to ensure perfect
adaptation. A proposed design of integral control for synthetic biological systems employs the …

… Olsman et al. chose to reveal their identities during the peer review process within this
peer review. Hansen et al. support the publication of this Peer Review; their permission to …