Digital medicine: a primer on measurement
Technology is changing how we practice medicine. Sensors and wearables are getting smaller
and cheaper, and algorithms are becoming powerful enough to predict medical outcomes…
and cheaper, and algorithms are becoming powerful enough to predict medical outcomes…
Chemokines and chemokine receptors in mucosal homeostasis at the intestinal epithelial barrier in inflammatory bowel disease
NP Zimmerman, RA Vongsa, MK Wendt… - Inflammatory bowel …, 2008 - academic.oup.com
Chemokines, a large family of small chemoattractive cytokines, and their receptors play an
integral role in the regulation of the immune response and homeostasis. The ability of …
integral role in the regulation of the immune response and homeostasis. The ability of …
Deep neural networks can predict new-onset atrial fibrillation from the 12-lead ECG and help identify those at risk of atrial fibrillation–related stroke
…, NJ Stoudt, G Schneider, KW Johnson, N Zimmerman… - Circulation, 2021 - Am Heart Assoc
Background: Atrial fibrillation (AF) is associated with substantial morbidity, especially when
it goes undetected. If new-onset AF could be predicted, targeted screening could be used to …
it goes undetected. If new-onset AF could be predicted, targeted screening could be used to …
Chemoprevention of esophageal cancer with black raspberries, their component anthocyanins, and a major anthocyanin metabolite, protocatechuic acid
DS Peiffer, NP Zimmerman, LS Wang… - Cancer prevention …, 2014 - AACR
Diets containing either freeze-dried black raspberries (BRBs) or their polyphenolic anthocyanins
(ACs) have been shown to inhibit the development of N-nitrosomethylbenzylamine (…
(ACs) have been shown to inhibit the development of N-nitrosomethylbenzylamine (…
[HTML][HTML] Earth mover's distance (EMD): a true metric for comparing biomarker expression levels in cell populations
DY Orlova, N Zimmerman, S Meehan, C Meehan… - PloS one, 2016 - journals.plos.org
… (Noah Zimmerman), which was accepted in 2011 by Stanford University and is available
online [14]. Reprinted from [14] under a CC BY license, with permission from Noah Zimmerman, …
online [14]. Reprinted from [14] under a CC BY license, with permission from Noah Zimmerman, …
Retracted: Dietary bacillus subtilis-based direct-fed microbials alleviate lps-induced intestinal immunological stress and improve intestinal barrier gene expression in …
UD Gadde, S Oh, Y Lee, E Davis, N Zimmerman… - 2017 - Elsevier
USDA identified a gap in the Institutional Animal Care and Use Committee (IACUC) approved
protocols for a published research report during normal oversight and review processes. …
protocols for a published research report during normal oversight and review processes. …
[HTML][HTML] CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis
Pancreatic ductal adenocarcinoma is an unsolved health problem with nearly 75% of patients
diagnosed with advanced disease and an overall 5-year survival rate near 5%. Despite …
diagnosed with advanced disease and an overall 5-year survival rate near 5%. Despite …
[HTML][HTML] CCR6 regulation of the actin cytoskeleton orchestrates human beta defensin-2-and CCL20-mediated restitution of colonic epithelial cells
RA Vongsa, NP Zimmerman, MB Dwinell - Journal of biological chemistry, 2009 - ASBMB
Intestinal inflammation is exacerbated by defects in the epithelial barrier and subsequent
infiltration of microbes and toxins into the underlying mucosa. Production of chemokines and …
infiltration of microbes and toxins into the underlying mucosa. Production of chemokines and …
rECHOmmend: an ECG-based machine learning approach for identifying patients at increased risk of undiagnosed structural heart disease detectable by …
Background: Timely diagnosis of structural heart disease improves patient outcomes, yet
many remain underdiagnosed. While population screening with echocardiography is …
many remain underdiagnosed. While population screening with echocardiography is …
Pancreatic cancer cell migration and metastasis is regulated by chemokine-biased agonism and bioenergetic signaling
Patients with pancreatic ductal adenocarcinoma (PDAC) invariably succumb to metastatic
disease, but the underlying mechanisms that regulate PDAC cell movement and metastasis …
disease, but the underlying mechanisms that regulate PDAC cell movement and metastasis …