Poliovirus disrupts nucleocytoplasmic trafficking and results in the cleavage of two nuclear
pore complex (NPC) proteins, Nup153 and Nup62. The NPC is a 125-MDa complex …

Stress granules are sites of mRNA storage formed in response to a variety of stresses,
including viral infections. Here, the mechanisms and consequences of stress granule formation …

Previous work has shown that several nucleoporins, including Nup62 are degraded in cells
infected with human rhinovirus (HRV) and poliovirus (PV) and that this contributes to the …

Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults
but can cause invasive disease, such as meningitis, in the newborn. To gain access to the …

Superantigens (SAgs) represent a diverse family of bacterial toxins that induce Vβ-specific T
cell proliferation associated with an array of important diseases in humans and animals, …

Many effects of the non-psychoactive cannabinoid, cannabidiol (CBD), have been described
in immune responses induced by strong immunological stimuli. It has also been shown that …

Staphylococcal superantigens (SAgs) are a family of secreted toxins that stimulate T cell
activation and are associated with an array of diseases in humans and livestock. Most SAgs …

Superantigens (SAgs) produced by Staphylococcus aureus at high concentrations induce
proliferation of T cells bearing specific TCR Vβ sequences and massive cytokinemia that …

Enteroviruses proteolyze nuclear pore complex (NPC) proteins (Nups) during infection, leading
to disruption of host nuclear transport pathways and alterations in nuclear permeability. …

Diabetic foot ulcer (DFU) is the most common and costly sequela of diabetes mellitus, often
leading to lower-extremity amputation with poor 5-year survival rates. Staphylococcus aureus …