The European Collaborative on Personalized Early Detection and Prevention of Breast Cancer
(ENVISION) brings together several international research consortia working on different …

Importance The age-based or “one-size-fits-all” breast screening approach does not take
into account the individual variation in risk. Mammography screening reduces death from …

The incidence of cancer is continuing to rise and risk-tailored early diagnostic and/or primary
prevention strategies are urgently required. The ideal risk-predictive test should: integrate …

Background: We modelled the efficiency of a personalised approach to screening for prostate
and breast cancer based on age and polygenic risk-profile compared with the standard …

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

Genome-wide association studies (GWAS) have identified 76 variants associated with
prostate cancer risk predominantly in populations of European ancestry. To identify additional …

Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide, and has a
strong heritable basis. We report a genome-wide association analysis of 34,627 CRC cases …

The COVID-19 pandemic affects mortality and morbidity, with disruptions expected to continue
for some time, with access to timely cancer-related services a concern. For breast cancer, …