Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

…, K Tanno, A Shimizu, T Yamaji, M Iwasaki, N Sawada… - Nature …, 2020 - nature.com
The overwhelming majority of participants in current genetic studies are of European ancestry.
To elucidate disease biology in the East Asian population, we conducted a genome-wide …

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

…, M Hirata, K Matsuda, M Iwasaki, T Yamaji, N Sawada… - Nature …, 2017 - nature.com
Obesity is a risk factor for a wide variety of health problems. In a genome-wide association
study (GWAS) of body mass index (BMI) in Japanese people (n = 173,430), we found 85 loci …

Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

…, J Seo, K Higasa, M Iwasaki, T Yamaji, N Sawada… - Nature …, 2020 - nature.com
To elucidate the genetics of coronary artery disease (CAD) in the Japanese population, we
conducted a large-scale genome-wide association study of 168,228 individuals of Japanese …

The JPHC study: design and some findings on the typical Japanese diet

S Tsugane, N Sawada - Japanese journal of clinical oncology, 2014 - academic.oup.com
The Japan Public Health Center-based prospective Study conducted a baseline survey for
140 000 registered residents aged 40–69 years within 11 public health center areas …

Validity of short and long self-administered food frequency questionnaires in ranking dietary intake in middle-aged and elderly Japanese in the Japan Public Health …

…, J Ishihara, Y Ishii, S Sasazuki, N Sawada… - Journal of …, 2016 - jstage.jst.go.jp
Background: Longitudinal epidemiological studies require both the periodic update of
intake information via repeated dietary survey and the minimization of subject burden in …

Consumption of n-3 fatty acids and fish reduces risk of hepatocellular carcinoma

N Sawada, M Inoue, M Iwasaki, S Sasazuki, T Shimazu… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Fish is a rich source of n-3 polyunsaturated fatty acids (PUFAs),
such as eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic …

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

…, M Hirata, K Matsuda, N Iwata, M Ikeda, N Sawada… - Nature …, 2019 - nature.com
To understand the genetics of type 2 diabetes in people of Japanese ancestry, we conducted
A meta-analysis of four genome-wide association studies (GWAS; 36,614 cases and …

Quality of diet and mortality among Japanese men and women: Japan Public Health Center based prospective study

…, A Goto, T Mizoue, M Noda, S Sasazuki, N Sawada… - bmj, 2016 - bmj.com
Objective To examine the association between adherence to the Japanese Food Guide
Spinning Top and total and cause specific mortality. Design Large scale population based …

[HTML][HTML] Association between type 2 diabetes and risk of cancer mortality: a pooled analysis of over 771,000 individuals in the Asia Cohort Consortium

…, E Saito, Y Lin, M Song, HN Luu, PC Gupta, N Sawada… - Diabetologia, 2017 - Springer
Aims/hypothesis The aims of the study were to evaluate the association between type 2
diabetes and the risk of death from any cancer and specific cancers in East and South Asians. …

Association of diabetes with all-cause and cause-specific mortality in Asia: a pooled analysis of more than 1 million participants

…, YL Qiao, MS Pednekar, J He, N Sawada… - JAMA network …, 2019 - jamanetwork.com
Importance Asia is home to the largest diabetic populations in the world. However, limited
studies have quantified the association of diabetes with all-cause and cause-specific mortality …